17 results on '"Ronkainen, A"'
Search Results
2. Stability of infundibular dilatations: a single center follow-up study and systematic review of the literature.
- Author
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Tarkiainen, Jeremias, Pyysalo, Liisa, Hinkka, Tero, Pienimäki, Juha-Pekka, Ronkainen, Antti, and Frösen, Juhana
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INTRACRANIAL aneurysms ,DIAGNOSTIC imaging ,MEDICAL records ,MEDICAL screening ,UNIVERSITY hospitals - Abstract
Purpose: Although infundibular dilatations (IDs) have been thought to be benign anatomical variants, case reports suggest that they can grow and rupture. The aim of this study was to determine whether IDs have a tendency to grow or rupture. Methods: The study population was collected from the Tampere University Hospital (TAUH) Aneurysm Database. The presence of IDs was screened from the medical records and imaging studies of 356 intracranial aneurysm patients left to follow-up from 2005 to 2020. The imaging studies were reviewed to confirm the IDs, and their clinical course. Finally, we performed a systematic review of published cases of ID leading to aneurysmatic rupture from PubMed. Results: We found 97 typical IDs in 83 patients and 9 preaneurysmal lesions resembling ID in 9 patients. Out of the typical cone-shaped IDs, none grew or ruptured in a total follow-up of 409 patient-years. One preaneurysmal lesion ruptured during a follow-up: this lesion had components of both infundibular dilatation and aneurysm at the beginning of follow-up. In the systematic literature search, we found 20 cases of aneurysmatic SAHs originating from an ID. Of those, only 7 had imaging available prerupture. All 7 IDs were typically cone-shaped, but a branching vessel originating from the apex of ID was only seen in 4/7. Conclusion: Typical infundibular dilatations seem to be benign anatomical variants that are stable and, thus, do not need prophylactic treatment or imaging follow-up. Likely, the SAHs reported from IDs were actually caused by misdiagnosed preaneurysmal lesions. [ABSTRACT FROM AUTHOR]
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- 2024
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3. The clinical course and outcomes of non-aneurysmal subarachnoid hemorrhages in a single-center retrospective study.
- Author
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Tarkiainen, Jeremias, Hovi, Valtteri, Pyysalo, Liisa, Ronkainen, Antti, and Frösen, Juhana
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CEREBRAL vasospasm ,SUBARACHNOID hemorrhage ,LOSS of consciousness ,LOGISTIC regression analysis ,MEDICAL records - Abstract
Background: Non-aneurysmal subarachnoid hemorrhages (SAHs) are thought to have a benign clinical course compared to aneurysmal SAHs. The aim of this study is to report the clinical course and outcomes of non-aneurysmal SAHs in a large single-center study. Methods: The patients with non-aneurysmal SAHs were screened from Tampere University Hospital from 2005 to 2020. The clinical data were collected from the patient's medical records and from the imaging studies. The primary interest was the neurological outcome assessed by dichotomized GOS at 2 months. Multivariable logistic regression was used to study the factors associated with unfavorable outcome. Results: We found 216 non-aneurysmal SAHs in 214 patients (2 patients with > 1 bleed). Ninety-seven percent of patients with a typical perimesencephalic bleeding pattern SAH (PSAH) (75/77) had a favorable outcome, while 86% of patients with non-perimesencephalic SAH (NPSAH) had a favorable outcome (84/98). In a multivariable logistic regression analysis, loss of consciousness (LOC) (aOR 214.67, 95% CI 17.62–2615.89) and Fisher grade 4 bleeding pattern (aOR 23.32, 95% CI 1.40–387.98) were associated with increased risk for unfavorable outcome (GOS 1–3). Vasospasm was seen in 20% of non-aneurysmal SAH patients, hydrocephalus in 17%, and 13% needed ventriculostomy. Conclusions: Non-aneurysmal SAH seems to have a good prognosis for majority of patients, especially for patients with a PSAH. Non-aneurysmal SAH patients are however affected by vasospasm and hydrocephalus and have similar risk factors for poor outcome as patients with aneurysmal SAH. This suggests that it is the severity of the bleed rather than the etiology that associates with poor outcome. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Facial nerve function and hearing after microsurgical removal of sporadic vestibular schwannomas in a population-based cohort
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Antti Ronkainen, Heikki Löppönen, Tuomas Rauramaa, Arto Immonen, Ismail Taha, Esa Mervaala, Jukka Huttunen, Nils Danner, Antti Hyvärinen, Olli-Pekka Kämäräinen, Antti Ranta, and Juha E. Jääskeläinen
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Microsurgery ,medicine.medical_specialty ,medicine.medical_treatment ,Population ,Schwannoma ,Facial nerve ,Radiosurgery ,030218 nuclear medicine & medical imaging ,Benign tumor ,Vestibulocochlear nerve ,03 medical and health sciences ,Vestibular schwannoma ,0302 clinical medicine ,Hearing ,medicine ,education ,Retrosigmoid approach ,Intraoperative monitoring ,education.field_of_study ,business.industry ,medicine.disease ,Surgery ,Original Article - Tumor - Schwannoma ,Neurology (clinical) ,Neurosurgery ,business ,030217 neurology & neurosurgery - Abstract
Background Vestibular schwannoma (VS) is a benign tumor originating from the vestibulocochlear nerve. The optimal treatment strategy is debated, since surgery may result in iatrogenic facial nerve injury. We report the results of VS surgery in a population-based unselected cohort in a center with access to Cyber Knife (CK) radiosurgery. Methods We reviewed 117 consecutive operations and found 95 patients who had their primary operation due to vestibular schwannoma between 2001 and 2017. Facial nerve function was evaluated with the House-Brackmann (HB) scale and hearing with the EU classification. Results The population consisted of 37 males and 58 females with a median age of 54 years (range 19–79). One year after surgery 67% of patients had a good outcome (HB 1–2). The rate of good outcome was 90% if no facial nerve damage was observed during intraoperative monitoring, the size of the tumor was under 30 mm and no hydrocephalus was present. During the study period, the treatment strategy changed from total to near-total resection after the introduction of CK radiosurgery, which could be used as a second-line treatment in case of residual tumor regrowth. This resulted in an improvement of outcomes (0% HB 5–6) despite the larger tumor sizes (25 ± 14 mm vs. 31 ± 9 mm, p
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- 2019
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5. Facial nerve function and hearing after microsurgical removal of sporadic vestibular schwannomas in a population-based cohort
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Taha, Ismail, primary, Hyvärinen, Antti, additional, Ranta, Antti, additional, Kämäräinen, Olli-Pekka, additional, Huttunen, Jukka, additional, Mervaala, Esa, additional, Löppönen, Heikki, additional, Rauramaa, Tuomas, additional, Ronkainen, Antti, additional, Jääskeläinen, Juha E., additional, Immonen, Arto, additional, and Danner, Nils, additional
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- 2019
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6. Procedural complications of endovascular treatment in patients with aneurysmal subarachnoid haemorrhage treated at a single centre
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Mikko Alanen, Juha Öhman, Oona Snicker, Antti Ronkainen, Liisa Pyysalo, Iiro Jalava, and Juha-Pekka Pienimäki
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Adult ,Male ,medicine.medical_specialty ,Neurology ,Aneurysm, Ruptured ,030218 nuclear medicine & medical imaging ,Brain Ischemia ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Aneurysm ,Postoperative Complications ,Risk Factors ,medicine ,Humans ,cardiovascular diseases ,Finland ,Neuroradiology ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Medical record ,Mortality rate ,Endovascular Procedures ,Interventional radiology ,Middle Aged ,Subarachnoid Hemorrhage ,medicine.disease ,Embolization, Therapeutic ,Surgery ,Treatment Outcome ,Female ,Neurology (clinical) ,Neurosurgery ,Complication ,business ,Intracranial Hemorrhages ,030217 neurology & neurosurgery - Abstract
We present a single-centre experience of procedural complications suffered by patients undergoing endovascular treatment for a ruptured saccular intracranial aneurysm at Tampere University Hospital, Finland, between 2000 and 2014. From 2000 to 2014, we treated 1,253 patients with aneurysmal subarachnoid haemorrhage, 491 of whom received endovascular treatment. Clinical data were collected retrospectively from the hospital’s aneurysm database. A procedural complication was defined as having occurred whenever there was a documented new event in the patient’s medical records or a note of a technical complication written by an interventionist after endovascular treatment. Procedural complications could be with or without clinical symptoms. Nearly 40% (491/1253) of the patients were treated with the endovascular method. Procedural complications occurred in 11.4% (56/491) of cases. The morbidity rate was 4.5% (22/491) and the mortality rate was 0.2% (1/491). Of the 56 complications, ischaemic complications occurred in 52% (29/56), haemorrhagic complications occurred in 27% (15/56) and technical complications occurred in 21% (12/56) of cases. In 61% (34/56) of the cases, the procedural complication did not cause any clinical symptoms. The total risk for procedural complications leading to postoperative disability or death at our institute was 4.7%. The complication frequency is in accordance with previous reports. Endovascular treatment of ruptured intracranial aneurysms is a safe treatment method when patient selection is carefully performed.
- Published
- 2017
7. Regional differences in the incidence of aneurysmal subarachnoid haemorrhage in Finland
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Juha E Öhman, Oona Snicker, Mikko Alanen, Liisa Pyysalo, Iiro Jalava, and Antti Ronkainen
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medicine.medical_specialty ,Pediatrics ,030204 cardiovascular system & hematology ,Aneurysm, Ruptured ,Cohort Studies ,Hospitals, University ,03 medical and health sciences ,0302 clinical medicine ,Aneurysm ,Epidemiology ,Medicine ,Humans ,cardiovascular diseases ,Finland ,Neuroradiology ,Retrospective Studies ,business.industry ,Incidence (epidemiology) ,Incidence ,Intracranial Aneurysm ,Subarachnoid Hemorrhage ,medicine.disease ,University hospital ,nervous system diseases ,Surgery ,Hospitalization ,Subarachnoid haemorrhage ,Neurology (clinical) ,Neurosurgery ,business ,030217 neurology & neurosurgery ,Regional differences - Abstract
Over the years, the consensus has generally been that Finland is a country with a significantly high incidence of aneurysmal subarachnoid haemorrhage (SAH) when compared to the rest of the world, excluding Japan. Most of the traditionally cited Finnish incidence studies are several decades old and have clear differences in their methodology and study design. The objective of this study was to determine the hospital-admitted incidence of aneurysmal SAH at Tampere University Hospital between 1990 and 2014. We also compared the incidence to other geographical regions in Finland. The material for this study consists of patients admitted to Tampere University Hospital between 1990 and 2014 with the presentation of aneurysmal SAH. There was a total of 1965 patients with aneurysmal SAH in our data. The mean hospital-admitted aneurysmal SAH incidence over the period was 7.41 per 100,000 person-years. The hospital-admitted aneurysmal SAH incidence in the Eastern Finland region was two-thirds greater than in the Tampere University Hospital region. We observed a relatively steady hospital-admitted incidence of aneurysmal SAH (7.41 per 100,000 person-years) in the Tampere University Hospital region. This result is parallel to a recent study looking into the incidence of aneurysmal SAH for the whole of Finland. Compared to the Tampere University Hospital region, the incidence was 64% greater in the Eastern Finland region.
- Published
- 2017
8. Facial nerve function and hearing after microsurgical removal of sporadic vestibular schwannomas in a population-based cohort.
- Author
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Taha, Ismail, Hyvärinen, Antti, Ranta, Antti, Kämäräinen, Olli-Pekka, Huttunen, Jukka, Mervaala, Esa, Löppönen, Heikki, Rauramaa, Tuomas, Ronkainen, Antti, Jääskeläinen, Juha E., Immonen, Arto, and Danner, Nils
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FACIAL nerve ,VESTIBULAR function tests ,ACOUSTIC nerve ,ACOUSTIC neuroma ,SCHWANNOMAS ,INTRAOPERATIVE monitoring - Abstract
Background: Vestibular schwannoma (VS) is a benign tumor originating from the vestibulocochlear nerve. The optimal treatment strategy is debated, since surgery may result in iatrogenic facial nerve injury. We report the results of VS surgery in a population-based unselected cohort in a center with access to Cyber Knife (CK) radiosurgery. Methods: We reviewed 117 consecutive operations and found 95 patients who had their primary operation due to vestibular schwannoma between 2001 and 2017. Facial nerve function was evaluated with the House-Brackmann (HB) scale and hearing with the EU classification. Results: The population consisted of 37 males and 58 females with a median age of 54 years (range 19–79). One year after surgery 67% of patients had a good outcome (HB 1–2). The rate of good outcome was 90% if no facial nerve damage was observed during intraoperative monitoring, the size of the tumor was under 30 mm and no hydrocephalus was present. During the study period, the treatment strategy changed from total to near-total resection after the introduction of CK radiosurgery, which could be used as a second-line treatment in case of residual tumor regrowth. This resulted in an improvement of outcomes (0% HB 5–6) despite the larger tumor sizes (25 ± 14 mm vs. 31 ± 9 mm, p < 0.05). Hearing preservation rates did not increase. Conclusions: Near-total resection and subsequent CK radiosurgery in case of residual tumor regrowth during follow-up seems to provide a good outcome of facial nerve function even in large VSs. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
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9. The impact of endovascular management on the outcome of aneurysmal subarachnoid hemorrhage in the elderly in Eastern Finland
- Author
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Timo Koivisto, Juha E. Jääskeläinen, Mohammad Khallaf, Mikael von und zu Fraunberg, Ritva Vanninen, Antti Ronkainen, Ilkka Parviainen, Juha Hernesniemi, Petros Nikolaos Karamanakos, Hannu Manninen, Jaakko Rinne, and Michael K. Morgan
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Adult ,Brain Infarction ,Male ,medicine.medical_specialty ,International Subarachnoid Aneurysm Trial ,Subarachnoid hemorrhage ,Vasodilator Agents ,medicine.medical_treatment ,Comorbidity ,medicine ,Humans ,Vasospasm, Intracranial ,cardiovascular diseases ,Aged ,Retrospective Studies ,Endovascular coiling ,medicine.diagnostic_test ,business.industry ,General surgery ,Endovascular Procedures ,Interventional radiology ,Retrospective cohort study ,Vasospasm ,Middle Aged ,Subarachnoid Hemorrhage ,Prognosis ,medicine.disease ,Surgery ,Cohort ,Female ,Neurology (clinical) ,Neurosurgery ,business - Abstract
The International Subarachnoid Aneurysm Trial (ISAT) concluded that "there is currently no reason to doubt that the reduction of dependent survival or death after endovascular coiling seen in all patients in the ISAT cohort should not be valid in the elderly". We feel that this generalization requires further investigation to assess its validity.We studied the impact of treatment era and independent risk factors for outcome in 179 consecutive elderly (or =70 years) aneurysmal subarachnoid hemorrhage (aSAH) patients admitted to Kuopio University Hospital either between 1983 and 1992 (Era I, n = 56), prior to the introduction of endovascular management, or between 1995 and 2004 (Era II, n = 123) when the endovascular treatment was established at our institute. Altogether 150 patients underwent occlusive aneurysm treatment, 47 clipping in the Era I as against 49 clipping, 49 endovascular therapy, and five combination therapy in the Era II.The 12-month survival (n = 179) did not improve from the Era I to the Era II. The proportion of good outcome (GOS IV-V) after occlusive therapy (n = 150) was equal in the Era I and Era II (n = 27/47; 57% vs. n = 56/103; 54%). In multivariate logistic regression analysis, independent predictors of poor outcome were age, poor grade (HuntHess IV-V), hydrocephalus, hypertension, and intraventricular hemorrhage, but not the mode of occlusive therapy (microsurgical vs. endovascular)Clinical severity of the SAH was the most significant predictor of outcome. Integration of coil treatment in clinical practice has not improved the overall outcome of aSAH in the elderly at our institute.
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- 2010
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10. Procedural complications of endovascular treatment in patients with aneurysmal subarachnoid haemorrhage treated at a single centre
- Author
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Alanen, Mikko, primary, Pyysalo, Liisa, additional, Jalava, Iiro, additional, Snicker, Oona, additional, Pienimäki, Juha-Pekka, additional, Öhman, Juha, additional, and Ronkainen, Antti, additional
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- 2017
- Full Text
- View/download PDF
11. Regional differences in the incidence of aneurysmal subarachnoid haemorrhage in Finland
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Jalava, Iiro, primary, Pyysalo, Liisa, additional, Alanen, Mikko, additional, Snicker, Oona, additional, Öhman, Juha, additional, and Ronkainen, Antti, additional
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- 2017
- Full Text
- View/download PDF
12. Procedural complications of endovascular treatment in patients with aneurysmal subarachnoid haemorrhage treated at a single centre.
- Author
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Alanen, Mikko, Pyysalo, Liisa, Jalava, Iiro, Snicker, Oona, Pienimäki, Juha-Pekka, Öhman, Juha, and Ronkainen, Antti
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SUBARACHNOID hemorrhage ,INTRACRANIAL aneurysms ,ENDOVASCULAR surgery ,MEDICAL databases ,MORTALITY - Abstract
Background: We present a single-centre experience of procedural complications suffered by patients undergoing endovascular treatment for a ruptured saccular intracranial aneurysm at Tampere University Hospital, Finland, between 2000 and 2014.Method: From 2000 to 2014, we treated 1,253 patients with aneurysmal subarachnoid haemorrhage, 491 of whom received endovascular treatment. Clinical data were collected retrospectively from the hospital’s aneurysm database. A procedural complication was defined as having occurred whenever there was a documented new event in the patient’s medical records or a note of a technical complication written by an interventionist after endovascular treatment. Procedural complications could be with or without clinical symptoms.Results: Nearly 40% (491/1253) of the patients were treated with the endovascular method. Procedural complications occurred in 11.4% (56/491) of cases. The morbidity rate was 4.5% (22/491) and the mortality rate was 0.2% (1/491). Of the 56 complications, ischaemic complications occurred in 52% (29/56), haemorrhagic complications occurred in 27% (15/56) and technical complications occurred in 21% (12/56) of cases. In 61% (34/56) of the cases, the procedural complication did not cause any clinical symptoms.Conclusions: The total risk for procedural complications leading to postoperative disability or death at our institute was 4.7%. The complication frequency is in accordance with previous reports. Endovascular treatment of ruptured intracranial aneurysms is a safe treatment method when patient selection is carefully performed. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
13. Subarachnoid haemorrhage of unknown aetiology
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Juha Hernesniemi and Antti Ronkainen
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Adult ,Male ,medicine.medical_specialty ,Aneurysm ,Humans ,Medicine ,cardiovascular diseases ,Aged ,Neuroradiology ,Neurologic Examination ,medicine.diagnostic_test ,business.industry ,Vascular disease ,Glasgow Outcome Scale ,Intracranial Aneurysm ,Middle Aged ,Subarachnoid Hemorrhage ,Bleed ,medicine.disease ,nervous system diseases ,Surgery ,Hypertension ,Angiography ,Etiology ,Female ,Neurology (clinical) ,Neurosurgery ,Tomography, X-Ray Computed ,business ,Follow-Up Studies - Abstract
Eighty-six of 996 patients with primary subarachnoid haemorrhage (SAH) had negative pan-angiography studies. These 86 patients with subarachnoid haemorrhage of unknown origin (SAH-NUD) were compared with 853 patients sustaining an aneurysmal bleed (SAH-A) admitted during the same period 1980-1989. The age and sex distribution of both groups were similar. The SAH-NUD group was in better condition on admission, with less blood evident on CT scan. All 16 (repeat control) angiography studies in the SAH-NUD group were negative. During a follow-up period ranging from 1 to 10 years (mean 5.4 years), two patients experienced rebleeding with negative repeat angiographies and subsequent total recovery. Using the Glasgow Outcome Scale (GOS) the final outcome was good in 86% of the study group and 54% of the aneurysm group. However, half of the SAH-NUD patients complained of persistent symptoms at long-term follow-up. Thus, despite a generally good prognosis, for a given individual SAH-NUD may be catastrophic with many residual symptoms persisting for the rest of the person's life.
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- 1992
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14. How often does an incomplete circle of Willis predispose to cerebral ischemia during closure of carotid artery? Postmortem and clinical imaging studies
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Antti Ronkainen, Kimmo Mäkinen, Ritva Vanninen, Hannu Manninen, and Harri Tulla
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Adult ,Male ,Models, Anatomic ,medicine.medical_specialty ,Adolescent ,Cerebral arteries ,Posterior cerebral artery ,Brain Ischemia ,Cerebral circulation ,Young Adult ,Postoperative Complications ,medicine.artery ,Internal medicine ,medicine ,Humans ,Carotid Stenosis ,Posterior communicating artery ,Vascular Patency ,Aged ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Brain ,Middle Aged ,Surgical Instruments ,Cerebral Angiography ,Causality ,Anterior communicating artery ,Carotid Arteries ,Cerebrovascular Circulation ,cardiovascular system ,Cardiology ,Circle of Willis ,Surgery ,Female ,Neurology (clinical) ,Autopsy ,Internal carotid artery ,business ,Vascular Surgical Procedures ,Cerebral angiography - Abstract
To evaluate the prevalence of anatomical variations in the circle of Willis predisposing to cerebral ischemia during intraoperative closure of a carotid artery. Anatomy of the cerebral arteries of 92 deceased was assessed by angiography and permanent silicone casts. Cerebral ischemia during closure of a carotid artery with patent contralateral internal carotid artery (ICA) was considered possible in cases of simultaneous nonfunctioning anterior communicating artery (diameter
- Published
- 2009
15. The impact of endovascular management on the outcome of aneurysmal subarachnoid hemorrhage in the elderly in Eastern Finland
- Author
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Karamanakos, Petros Nikolaos, primary, Koivisto, Timo, additional, Vanninen, Ritva, additional, Khallaf, Mohammad, additional, Ronkainen, Antti, additional, Parviainen, Ilkka, additional, Manninen, Hannu, additional, von und zu Fraunberg, Mikael, additional, Morgan, Michael K., additional, Jaaskelainen, Juha E., additional, Hernesniemi, Juha, additional, and Rinne, Jaakko, additional
- Published
- 2010
- Full Text
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16. How often does an incomplete circle of Willis predispose to cerebral ischemia during closure of carotid artery? Postmortem and clinical imaging studies
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Manninen, Hannu, primary, Mäkinen, Kimmo, additional, Vanninen, Ritva, additional, Ronkainen, Antti, additional, and Tulla, Harri, additional
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- 2009
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17. Subarachnoid haemorrhage of unknown aetiology
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Ronkainen, A., primary and Hernesniemi, J., additional
- Published
- 1992
- Full Text
- View/download PDF
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