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Your search keyword '"Arita, Hideyuki"' showing total 4 results
Start Over Author "Arita, Hideyuki" Journal acta neuropathologica communications
4 results on '"Arita, Hideyuki"'

1. Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospective cohort

Author

Hayashi, Nobuhide, Fukai, Junya, Nakatogawa, Hirokazu, Kawaji, Hiroshi, Yoshioka, Ema, Kodama, Yoshinori, Nakajo, Kosuke, Uda, Takehiro, Naito, Kentaro, Kijima, Noriyuki, Okita, Yoshiko, Kagawa, Naoki, Takahashi, Yoshinobu, Hashimoto, Naoya, Arita, Hideyuki, Takano, Koji, Sakamoto, Daisuke, Iida, Tomoko, Arakawa, Yoshiki, Kawauchi, Takeshi, Sonoda, Yukihiko, Mitobe, Yuta, Ishibashi, Kenichi, Matsuda, Masahide, Achiha, Takamune, Tomita, Takahiro, Nonaka, Masahiro, Hara, Keijiro, Takebe, Noriyoshi, Tsuzuki, Takashi, Nakajima, Yoshikazu, Ohue, Shiro, Nakajima, Nobuyuki, Watanabe, Akira, Inoue, Akihiro, Umegaki, Masao, Kanematsu, Daisuke, Katsuma, Asako, Sumida, Miho, Shofuda, Tomoko, Mano, Masayuki, Kinoshita, Manabu, Mori, Kanji, Nakao, Naoyuki, and Kanemura, Yonehiro

Published
2024
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2. TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations.

Author

Arita, Hideyuki, Matsushita, Yuko, Machida, Ryunosuke, Yamasaki, Kai, Hata, Nobuhiro, Ohno, Makoto, Yamaguchi, Shigeru, Sasayama, Takashi, Tanaka, Shota, Higuchi, Fumi, Iuchi, Toshihiko, Saito, Kuniaki, Kanamori, Masayuki, Matsuda, Ken-Ichiro, Miyake, Yohei, Tamura, Kaoru, Tamai, Sho, Nakamura, Taishi, Uda, Takehiro, Okita, Yoshiko, Fukai, Junya, Sakamoto, Daisuke, Hattori, Yasuhiko, Pareira, Eriel, Hatae, Ryusuke, Ishi, Yukitomo, Miyakita, Yasuji, Tanaka, Kazuhiro, Takayanagi, Shunsaku, Otani, Ryohei, Sakaida, Tsukasa, Kobayashi, Keiichi, Saito, Ryuta, Kurozumi, Kazuhiko, Shofuda, Tomoko, Nonaka, Masahiro, Suzuki, Hiroyoshi, Shibuya, Makoto, Komori, Takashi, Sasaki, Hikaru, Mizoguchi, Masahiro, Kishima, Haruhiko, Nakada, Mitsutoshi, Sonoda, Yukihiko, Tominaga, Teiji, Nagane, Motoo, Nishikawa, Ryo, Kanemura, Yonehiro, Kuchiba, Aya, Narita, Yoshitaka, and Ichimura, Koichi

Subjects
1p/19q codeletion, CDKN2A, Glioma, IDH1/2, TERT, Adolescent, Adult, Aged, Aged, 80 and over, Astrocytoma, Brain Neoplasms, Chromosome Deletion, Chromosomes, Human, Pair 1, Chromosomes, Human, Pair 19, Female, Glioblastoma, Glioma, Humans, Isocitrate Dehydrogenase, Karnofsky Performance Status, Male, Middle Aged, Multivariate Analysis, Mutation, Neoplasm Grading, Neurosurgical Procedures, Oligodendroglioma, Prognosis, Promoter Regions, Genetic, Proportional Hazards Models, Radiotherapy, Adjuvant, Retrospective Studies, Survival Rate, Telomerase, Young Adult
Abstract

TERT promoter mutations are commonly associated with 1p/19q codeletion in IDH-mutated gliomas. However, whether these mutations have an impact on patient survival independent of 1p/19q codeletion is unknown. In this study, we investigated the impact of TERT promoter mutations on survival in IDH-mutated glioma cases. Detailed clinical information and molecular status data were collected for a cohort of 560 adult patients with IDH-mutated gliomas. Among these patients, 279 had both TERT promoter mutation and 1p/19q codeletion, while 30 had either TERT promoter mutation (n = 24) or 1p/19q codeletion (n = 6) alone. A univariable Cox proportional hazard analysis for survival using clinical and genetic factors indicated that a Karnofsky performance status score (KPS) of 90 or 100, WHO grade II or III, TERT promoter mutation, 1p/19q codeletion, radiation therapy, and extent of resection (90-100%) were associated with favorable prognosis (p

Published
2020

3. Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts

Author

Umehara, Toru, primary, Arita, Hideyuki, additional, Yoshioka, Ema, additional, Shofuda, Tomoko, additional, Kanematsu, Daisuke, additional, Kinoshita, Manabu, additional, Kodama, Yoshinori, additional, Mano, Masayuki, additional, Kagawa, Naoki, additional, Fujimoto, Yasunori, additional, Okita, Yoshiko, additional, Nonaka, Masahiro, additional, Nakajo, Kosuke, additional, Uda, Takehiro, additional, Tsuyuguchi, Naohiro, additional, Fukai, Junya, additional, Fujita, Koji, additional, Sakamoto, Daisuke, additional, Mori, Kanji, additional, Kishima, Haruhiko, additional, and Kanemura, Yonehiro, additional

Published
2019
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4. A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas

Author

Arita, Hideyuki, primary, Yamasaki, Kai, additional, Matsushita, Yuko, additional, Nakamura, Taishi, additional, Shimokawa, Asanao, additional, Takami, Hirokazu, additional, Tanaka, Shota, additional, Mukasa, Akitake, additional, Shirahata, Mitsuaki, additional, Shimizu, Saki, additional, Suzuki, Kaori, additional, Saito, Kuniaki, additional, Kobayashi, Keiichi, additional, Higuchi, Fumi, additional, Uzuka, Takeo, additional, Otani, Ryohei, additional, Tamura, Kaoru, additional, Sumita, Kazutaka, additional, Ohno, Makoto, additional, Miyakita, Yasuji, additional, Kagawa, Naoki, additional, Hashimoto, Naoya, additional, Hatae, Ryusuke, additional, Yoshimoto, Koji, additional, Shinojima, Naoki, additional, Nakamura, Hideo, additional, Kanemura, Yonehiro, additional, Okita, Yoshiko, additional, Kinoshita, Manabu, additional, Ishibashi, Kenichi, additional, Shofuda, Tomoko, additional, Kodama, Yoshinori, additional, Mori, Kanji, additional, Tomogane, Yusuke, additional, Fukai, Junya, additional, Fujita, Koji, additional, Terakawa, Yuzo, additional, Tsuyuguchi, Naohiro, additional, Moriuchi, Shusuke, additional, Nonaka, Masahiro, additional, Suzuki, Hiroyoshi, additional, Shibuya, Makoto, additional, Maehara, Taketoshi, additional, Saito, Nobuhito, additional, Nagane, Motoo, additional, Kawahara, Nobutaka, additional, Ueki, Keisuke, additional, Yoshimine, Toshiki, additional, Miyaoka, Etsuo, additional, Nishikawa, Ryo, additional, Komori, Takashi, additional, Narita, Yoshitaka, additional, and Ichimura, Koichi, additional

Published
2016
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