1. Obstetric synthetic oxytocin use and subsequent hyperactivity/inattention problems in Danish children
- Author
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Mette Juhl, Carsten Obel, Katrine Strandberg-Larsen, Nicole Nadine Lønfeldt, Lonny Stokholm, and Susanne Hvolgaard Mikkelsen
- Subjects
Adult ,Male ,medicine.medical_specialty ,Offspring ,Denmark ,Logistic regression ,Oxytocin ,Danish ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,Birth register ,Pregnancy ,Surveys and Questionnaires ,augmentation ,oxytocin ,medicine ,Attention deficit hyperactivity disorder ,Humans ,030212 general & internal medicine ,Registries ,Child ,induction ,strengths and difficulties questionnaire ,030219 obstetrics & reproductive medicine ,Obstetrics ,business.industry ,Obstetrics and Gynecology ,hyperactivity/inattention ,General Medicine ,Strengths and Difficulties Questionnaire ,Odds ratio ,medicine.disease ,language.human_language ,030227 psychiatry ,attention deficit hyperactivity disorder ,Attention Deficit Disorder with Hyperactivity ,language ,Female ,Birth cohort ,business ,Clinical psychology ,medicine.drug - Abstract
INTRODUCTION: The objective was to examine the association between obstetric synthetic oxytocin use and hyperactivity/inattention problems in offspring.MATERIAL AND METHODS: We identified children born in 2000-2003, enrolled in the Danish National Birth Cohort, with data on the Strengths and Difficulties Questionnaire (SDQ) reported by parents at age seven (n = 33 896) and age 11 (n = 27 561) and the children themselves around age 11 (n = 27 251). Information on oxytocin administration was provided in the Medical Birth Register. We estimated mean differences and odds ratios for childhood hyperactivity/inattention problems according to oxytocin exposure.RESULTS: Synthetic oxytocin was administered in 26% of the deliveries. We did not find the use of synthetic oxytocin during birth to be associated with childhood hyperactivity/inattention problems, whether analyzed in linear or logistic regression models.CONCLUSIONS: Our findings do not support any effects of obstetric use of synthetic oxytocin on hyperactivity/inattention problems in children when measured with the SDQ subscale at 7 or 11 years of age.
- Published
- 2018
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