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Your search keyword '"Alessio Montuoro"' showing total 2 results
Start Over Author "Alessio Montuoro" Journal acta ophthalmologica
2 results on '"Alessio Montuoro"'

1. Ganglion cell layer thickening in well-controlled patients with type 1 diabetes: an early sign for diabetic retinopathy?

Author

Ursula Schmidt-Erfurth, Christian Pruente, Henryk Zulewski, Roger Lehmann, Alexandra Kaider, Katja Hatz, Bianca S Gerendas, and Alessio Montuoro

Subjects
Adult, Male, Retinal Ganglion Cells, medicine.medical_specialty, chemistry.chemical_compound, image analysis, Diabetes mellitus, Ophthalmology, Statistical significance, medicine, Humans, early detection, Ganglion cell layer, Type 1 diabetes, Analysis of Variance, Diabetic Retinopathy, business.industry, early disease, Retinal, General Medicine, Diabetic retinopathy, Original Articles, Middle Aged, medicine.disease, medicine.anatomical_structure, Cross-Sectional Studies, Diabetes Mellitus, Type 1, chemistry, OCT, Case-Control Studies, Female, Original Article, Thickening, Analysis of variance, sense organs, business, Tomography, Optical Coherence
Abstract

Purpose To evaluate early changes in retinal layers using optical coherence tomography (OCT) in patients with long‐standing type 1 diabetes (DM1) receiving intensified insulin therapy. Methods In a cross‐sectional case–control study 150 patients with DM1 and 150 age‐ and sex‐matched healthy control participants underwent OCT imaging. Scans of both eyes were analysed for different layers (NFL, GCL (+IPL), INL, outer layer complex (OLC, including OPL, ONL and ELM) and photoreceptors (PR)) in all subfields of an ETDRS grid. All analyses were performed semi‐automatically using custom software by certified graders of the Vienna Reading Center. ANOVA models were used to compare the mean thickness of the layers between patients and controls. Results Six hundred eyes with 512 datapoints in 49 b‐scans in each OCT were analysed. Mean thickness in patients/controls was 31.35 μm/30.65 μm (NFL, p = 0.0347), 76.7 μm/73.15 μm (GCL, p ≤ 0.0001), 36.29 μm/37.13 μm (INL, p = 0.0116), 114.34 μm/112.02 μm (OLC, p

Published
2019

2. Visual acuity and microperimetric mapping of lesion area in eyes with inflammatory cystoid macular oedema

Author

Marion R. Munk, Alessio Montuoro, Ursula Schmidt-Erfurth, Michael Larsen, Wolfgang Huf, Florian Sulzbacher, Maria Elisabeth Kroh, and Christopher G. Kiss

Subjects
Male, medicine.medical_specialty, Fovea Centralis, Visual acuity, genetic structures, Visual Acuity, Macular Edema, Retina, Lesion, Uveitis, chemistry.chemical_compound, Ophthalmology, Edema, medicine, Humans, Fluid accumulation, Prospective Studies, business.industry, Subretinal Fluid, Retinal, General Medicine, Middle Aged, eye diseases, Cross-Sectional Studies, chemistry, Cystoid macular oedema, Visual Field Tests, Female, sense organs, Thickening, medicine.symptom, Visual Fields, business, Microperimetry, Tomography, Optical Coherence
Abstract

Purpose: To evaluate the effect of fluid accumulation on local visual function in inflammatory cystoid-macular-edema (ICME). Methods: This cross-sectional study applied optical-coherence-tomography over a 12 × 12 fovea-centered field in 50 patients with ICME and mapped the extent of fluid-filled spaces in various retinal layers, of subretinal-fluid and of diffuse-edema. Regression analysis examined effect of planimetric fluid-distribution on best-corrected-visual-acuity (BCVA) and mean microperimetric-sensitivity. Results: BCVA decreased with increasing central-neuroretinal-thickness (r = 0.52, p = 0.001), total central-retinal-thickness, including subneuroretinal-fluid (r = 0.41, p = 0.006), total cystoid-and-diffuse edema-area (r = 0.35, p = 0.036) and cystoid inner-nuclear-layer area (r = 0.39, p = 0.02). Mean retinal-sensitivity decreased with increasing diffuse edema-area (r = −0.86, p

Published
2013

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