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Your search keyword '"Marek, Polak"' showing total 3 results
Start Over Author "Marek, Polak" Journal acta oto-laryngologica
3 results on '"Marek, Polak"'

1. Electrode estimation in the acoustic region of the human Cochlea

Author

Artur Lorens, Marek Polak, Henryk Skarżyński, and Mariusz Furmanek

Subjects
Adult, Electric acoustic stimulation, Materials science, Acoustics, behavioral disciplines and activities, 03 medical and health sciences, 0302 clinical medicine, Audiometry, otorhinolaryngologic diseases, Humans, Hearing Loss, 030223 otorhinolaryngology, Cochlea, Hearing preservation, Reproducibility of Results, General Medicine, Cochlear Implantation, Electric Stimulation, Cochlear Implants, Acoustic Stimulation, Otorhinolaryngology, 030220 oncology & carcinogenesis, Electrode, sense organs, psychological phenomena and processes
Abstract

Background: In this study, a method to estimate number of electrodes in the acoustic region of Electric Acoustic Stimulation (EAS) subjects was proposed. Aims/Objectives: To develop and validate an...

Published
2020
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2. Cochlear Implants in Children--A Review

Author

Adrien A. Eshraghi, Marek Polak, Thomas J. Balkany, Jack E. King, Jennifer Lingvai, Annelle V. Hodges, Stacy Butts, and Kathy Bricker

Subjects
medicine.medical_specialty, medicine.medical_treatment, education.educational_degree, Deafness, Audiology, Habilitation, X ray computed, Cochlear implant, otorhinolaryngologic diseases, medicine, Humans, Child, Cochlear implantation, education, business.industry, Rehabilitation, General Medicine, Cochlear Implantation, Magnetic Resonance Imaging, Otorhinolaryngology, Child, Preschool, Ear, Inner, Candidacy, sense organs, Sensory hearing loss, Tomography, X-Ray Computed, business
Abstract

Over the past two decades, cochlear implantation has become a widely accepted treatment of deafness in children. Over 20,000 children have received cochlear implants worldwide. Hearing, language and social development outcomes have been positive. We review current issues in cochlear implantation, candidacy, evaluation, surgery, habilitation, ethics and outcomes.

Published
2002
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3. Triamcinolone acetonide protects auditory hair cells from 4-hydroxy-2,3-nonenal (HNE) ototoxicity in vitro

Author

Jose Ruiz, Jose F. Guzman, Marek Polak, Carolyn Garnham, Thomas R. Van De Water, Thomas J. Balkany, and Adrien A. Eshraghi

Subjects
medicine.medical_specialty, Triamcinolone acetonide, medicine.drug_class, Cochlear Diseases, Pharmacology, Biology, In Vitro Techniques, Organ culture, medicine.disease_cause, Triamcinolone Acetonide, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Ototoxicity, Nonenal, Hair Cells, Auditory, otorhinolaryngologic diseases, medicine, Animals, 030223 otorhinolaryngology, Glucocorticoids, Organ of Corti, Aldehydes, integumentary system, General Medicine, medicine.disease, In vitro, Surgery, Rats, Oxidative Stress, medicine.anatomical_structure, Otorhinolaryngology, 030220 oncology & carcinogenesis, Corticosteroid, sense organs, Oxidative stress, medicine.drug
Abstract

Triamcinolone acetonide crystalline suspension (e.g. Volon A) was not ototoxic to the auditory hair cells present within organ of Corti explants and protected them from an ototoxic molecule, i.e. 4-hydroxy-2,3-nonenal (HNE), that is produced within the organ of Corti as a result of oxidative stress-induced damage.To test the corticosteroid, triamcinolone acetonide, for ototoxicity and otoprotective capacity in organ of Corti explants.Organ of Corti explants excised from 4-day-old rats were the test system, HNE was the ototoxin challenge. Hair cell integrity counts were performed with fluorescent microscopy on fixed explants stained with FITC-labeled phalloidin. Statistical significance was set at p0.05.Triamcinolone acetonide did not affect hair cell integrity in the organ of Corti explants and it provided a high level of protection of hair cells against the ototoxic effects of a damaging level of HNE as determined by hair cell density counts.

Published
2006

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