1. Astrovirus and digestive disorders in neonatal units
- Author
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Céline Chappé, Patrick Pladys, Laetitia Morel, Sophie Minjolle, Ronald Colimon, and Alain Dabadie
- Subjects
medicine.medical_specialty ,Pediatrics ,Gastroenterology ,Astrovirus ,03 medical and health sciences ,fluids and secretions ,0302 clinical medicine ,030225 pediatrics ,Internal medicine ,medicine ,Feces ,0303 health sciences ,biology ,030306 microbiology ,business.industry ,Gestational age ,General Medicine ,Human astrovirus ,medicine.disease ,biology.organism_classification ,3. Good health ,Bloody ,Neonatal infection ,Pediatrics, Perinatology and Child Health ,Necrotizing enterocolitis ,business - Abstract
Aim: To describe clinical signs associated with Human Astrovirus (HAstV) in stools in neonatal units. Methods: During 2005–2006, all stool virology performed for isolated digestive symptoms or suspicion of neonatal infection was tested for HAstV by an amplified enzyme-linked immunoassay (IDEIA™ Astrovirus test, Dako Cytomation). Each newborn with a positive result (HAstV+ group) was retrospectively matched with the first following symptomatic newborn in the same care unit having a negative stool virology (HAstV− group). Clinical data were collected during two 3-day periods (just after faecal samples collection and 1 week before) and compared within and between each group. Results: Human astrovirus was detected in faeces of 68 newborns [gestational age: 31.4(28.8–34) weeks] at a post-natal age of 23 (15–42) days without seasonal dominance. Human astrovirus+ and HAstV− groups were comparable. Bloody stool (54.4% versus 14.7%, p
- Published
- 2012
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