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Adult male non-descript bred dog presented with a history of circling motion, frequent head nodding, crusty muzzle, muscle twitching, seizure, vomiting, inappetence, coughing, inability to walk, watery pustular discharge from eyes and blood stained left ears and on further examination of foot pads showed thick, crusty or hardened sole and based on the clinical signs and symptoms, provisionally diagnosed as Canine distemper and advised euthanasia due to close geographic onset of the disease epidemic and to prevent Canine distemper-associated deaths in wild canids and felids.