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The objective of this study is to examine the protection effect of CPCC treatment in hepatic injury and the role of Calreticulin (CRT) in hepatic injury. The control and alloxan groups were given water and the CPCC group was given CPCC (Cr3+40μg/kg.d) every day, respectively. After 4 weeks, the alloxan and CPCC groups were injected with alloxan (40mg/kg) for 6d. Total protein was extracted from mice liver. SDS-PAGE and two-dimensional electrophoresis (2-DE) were performed in this study from the total protein of mice hepatic. The samples of 2-DE were analyzed through Time of Flight Mass Spectrometer . The mRNA of CRT was detected using fluorescence quantitative polymerase chain reaction (qPCR) in mice liver. The results of 2-DE and qPCR showed the expression of CRT had significant difference among controlalloxan and CPCC mice both on the transcriptional and protein levels. CRT is a potential target as the roles of treatment and prevention in hepatic injury. CPCC is expected to become new health product for prevention and treatment of the hepatic injury.

In this paper, BiFeO3 (BFO) films were grown on LaAlO3 (LAO) substrate by a RF magnetron sputtering system. Fabrication parameters, such as work pressure, sputtering atmosphere, and post annealing were examined in terms of their influences on characteristics of the ferroelectric films. X-Ray diffraction, Raman scattering and scanning electron microscope measurements were employed to characterize the microstructure and the morphology of these films. At last, the ferroelectric characteristic of BFO has been studied, and the film has a large saturated polarization of 40 μC / cm2 under an applied field of 12 kV /cm.

The single-phase multiferroic Bi1-xSbxFeO3 ceramics were fabricated using traditional solid phase reaction technique and the effects of Sb3+ doping on their crystal structure and ferroelectric behavior were studied. X-ray diffraction (XRD) measurement revealed that 830°C is an appropriate sintering temperature for forming a pure-phase of Bismuth ferrite structure. The average crystalline grain size of doped ceramics becomes smaller as the doping concentration x increases. The leakage current of doped sample was much reduced compared with that of BFO. The electric hysteresis loops were obtained in the Bi1-xSbxFeO3 (x=0.02), and the residual polarization and saturated polarization are 0.03 μC/cm2 and 0.337 μC/cm2, respectively.

When a steel etc. a ferromagnetic material is subjected to the external loads, the internal force will develop, that is, stress will develop inside the material, which will lead to a corresponding change in the magnetic permeability of this material when magnetized. In this paper, according to this unique property of the ferromagnetic material, in the light of the mainly stressed and deformation characteristic of a long span steel structure etc. defect sensitive structures, by the use of stress sensitivity of magnetization, a mathematical physical model of relationship between the change in the magnetic permeability and stress is studied and put forward when a ferromagnetic component is under the action of a simple stress, a linear dependency relation of the component’s stress and its permeability is obtained, and the fundamental theory of the magnetic non-destructive testing of a safe state and its engineering application method is also established for a long span steel structure etc. defect sensitive structures, which provides a definite basis for guaranteeing safety of this kind of structures. Additionally, in this paper through the comparison of the theoretical analysis results with results of the related experiments, the dependency relation of change in the magnetic permeability and stress etc. theoretical research results is verified. Both these results exhibit a good consistence, which demonstrates that the research and the application of the non-destructive safe testing method for a defect sensitive structure based on the magnetic effect is feasible and valid and the future will see a certain engineering application prospect in this research and this testing method.

A new improved multidiscipline feasible (MDF) strategy based on the updating approximate function constructed by Response Surface Method (RSM) is firstly pointed out and denoted as MDF-update-RSM which involves double cycles. Before the start of inner loop on MDF-update-RSM strategy, the approximate function is initialized by RSM on a set of sampling points which are generated from the Design of Experiment (DOE). With the process of outer loop, the coefficients and one high-order term of polynomial are updated and upgrade by the Least Square Regression. The ability of this new strategy promotes the efficiency and saves huge calculational cost incurred by the MDF strategy which always runs on the multidisciplinary analysis (MDA). The MDF-update-RSM is good procedure to ameliorate the accuracy that has been tested by the Rosenbrock function in this paper. Finally, the optimization strategy is employed on executing the low pressure turbine shrouded blade design and provides a true optimal result compared to the classical MDF strategy.