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5 results on '"Eric Watier"'

1. Is Abdominoplasty and Concomitant Laparoscopic Umbilical Hernia Repair Feasible by a Plastic Surgeon?

Author

Damien Bergeat, Camille Mocquard, Nicolas Bertheuil, Eric Watier, Farid Bekara, CHU Pontchaillou [Rennes], Microenvironment, Cell Differentiation, Immunology and Cancer (MICMAC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Hôpital Lapeyronie [Montpellier] (CHU), and Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
medicine.medical_specialty, Umbilical surgery, medicine.medical_treatment, [SDV.CAN]Life Sciences [q-bio]/Cancer, 030230 surgery, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Umbilical hernia repair, medicine, Humans, Hernia, Laparoscopy, ComputingMilieux_MISCELLANEOUS, Surgeons, Abdominoplasty, medicine.diagnostic_test, business.industry, General Medicine, medicine.disease, 3. Good health, Surgery, Plastic surgery, Concomitant, business, Hernia, Umbilical
Abstract

International audience

Published
2019
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2. Medial Thigh Lift for Patients Following Massive Weight Loss: Our Postbariatric Experience

Author

Nicolas Bertheuil, Nicolas Isola, and Eric Watier

Subjects
Thigh surgery, medicine.medical_specialty, business.industry, Lift (data mining), Dermatologic Surgical Procedures, Bariatric Surgery, General Medicine, 030230 surgery, Medial compartment of thigh, Surgery, 03 medical and health sciences, 0302 clinical medicine, Thigh, Weight loss, 030220 oncology & carcinogenesis, Weight Loss, Humans, Medicine, medicine.symptom, business
Published
2018
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3. Liposuction Preserves the Morphological Integrity of the Microvascular Network: Flow Cytometry and Confocal Microscopy Evidence in a Controlled Study

Author

Cédric Ménard, Eric Watier, Benoit Chaput, Jean-Louis Grolleau, Frédéric Mourcin, Karin Tarte, Audrey Varin, Sandra Berger-Müller, Ignacio Garrido, Nicolas Bertheuil, Luc Sensebé, Service de chirurgie plastique, reconstructive et esthétique [Rennes] = Cosmetic Reconstructive and Plastic surgery [Rennes], CHU Pontchaillou [Rennes], EFS, Microenvironnement et cancer (MiCa), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Etablissement Français du Sang Bretagne, Service de Chirurgie Plastique, Chirurgie plastique, CHU Toulouse [Toulouse]-Hôpital de Rangueil, CHU Toulouse [Toulouse], Service de Chirurgie Oncologique, Institut Claudius Regaud, Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), STROMALab, Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Etablissement Français du Sang-Institut National de la Santé et de la Recherche Médicale (INSERM), ANR-10-IBHU-0005, European Center for Transplantation Sciences and Immunotherapy, Médaille d'or from Rennes University Hospital, ANR-10-IBHU-0005,CESTI (TSI-IHU),Centre Européen des Sciences de la Transplantation et de l'Immunothérapie (TSI-IHU)(2010), Service de chirurgie plastique, reconstructive et esthétique, Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CHU Pontchaillou [Rennes]-Hôpital Sud, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement Français du Sang-Centre National de la Recherche Scientifique (CNRS), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Service Chirurgie plastique - brûlés [CHU Toulouse], Pôle Urologie - Néphrologie - Dialyse - Transplantations - Brûlés - Chirurgie plastique - Explorations fonctionnelles et physiologiques [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), and Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement Français du Sang-Centre National de la Recherche Scientifique (CNRS)

Subjects
Adult, Male, CD31, medicine.medical_specialty, Pathology, [SDV]Life Sciences [q-bio], medicine.medical_treatment, Urology, Adipose tissue, 030230 surgery, Flow cytometry, law.invention, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Lipectomy, Confocal microscopy, law, Adipocyte, Adipocytes, medicine, Humans, Microscopy, Confocal, medicine.diagnostic_test, business.industry, Abdominoplasty, Endothelial Cells, General Medicine, Middle Aged, Flow Cytometry, Plastic surgery, Microvascular Network, Adipose Tissue, chemistry, 030220 oncology & carcinogenesis, Liposuction, Microvessels, Female, Surgery, business
Abstract

International audience; BACKGROUND: Liposuction is a very popular technique in plastic surgery that allows for the taking adipose tissue (AT) on large surfaces with little risk of morbidity. Although liposuction was previously shown to preserve large perforator vessels, little is known about the effects of liposuction on the microvasculature network. OBJECTIVES: The aim of this study was to analyze the effect of liposuction on the preservation of microvessels at tissue and cellular levels by flow cytometry and confocal microscopy following abdominoplasty procedure. METHODS: Percentage of endothelial cells in AT from liposuction and en bloc AT was determined by multicolor flow cytometry. Moreover, vessel density and adipocyte content were analyzed in situ in 3 different types of AT (en bloc, from liposuction, and residual AT after liposuction) by confocal microscopy. RESULTS: Flow cytometric analysis showed that en bloc AT contained 30.6% ± 12.9% and AT from liposuction 21.6% ± 9.9% of endothelial cells (CD31(pos)/CD45(neg)/CD235a(neg)/CD11b(neg)) (P = .009). Moreover, analysis of paired AT from the same patients (n = 5) confirmed a lower percentage of endothelial cells in AT from liposuction compared to en bloc AT (17.7% ± 4.5% vs 21.9% ± 3.3%, P = .031). Likewise, confocal microscopy showed that en bloc AT contained 8.2% ± 6.3%, AT from liposuction only 1.6% ± 1.0% (P \textless .0001), and AT after liposuction 8.9% ± 4.1% (P = .111) of CD31(pos) vessels. Conversely, adipocyte content was 39.5% ± 14.5% in the en bloc AT, 45% ± 18.4% in AT from liposuction (P = .390), and 18.8 ± 14.8% in AT after liposuction (P = .011). CONCLUSIONS: For the first time, we demonstrate that liposuction preserves the microvascular network. Indeed, a low percentage of endothelial cells was found in AT from liposuction and we confirm the persistence of microvessels in the tissue after liposuction

Published
2015
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4. Comments on 'What is Wrong With Systematic Reviews and Meta-Analyses: If You Want the Right Answer, Ask the Right Question!'

Author

Eric Watier, Nicolas Bertheuil, Raphael Carloni, and Florian Naudet

Subjects
medicine.medical_specialty, Evidence-Based Medicine, business.industry, Alternative medicine, Subject (documents), General Medicine, Evidence-based medicine, 030230 surgery, Clinical Practice, 03 medical and health sciences, 0302 clinical medicine, Systematic review, Ask price, medicine, Humans, Surgery, Engineering ethics, 030212 general & internal medicine, business, Research question, Lower trunk
Abstract

We read with great interest the recently published Evidence Based Medicine (EBM) Hub article entitled “What is Wrong With Systematic Reviews and Meta-Analyses: If You Want the Right Answer, Ask the Right Question!” by Thoma and Eaves.1 We agree with most of the comments on the limitations of our study.2 Indeed, their didactic article drew attention to important methodologies that need to be adopted when appraising systematic reviews and meta-analyses. These methodologies allow non-statisticians to become more familiar with such papers, which are being published with increasing frequency in plastic surgery journals. For every scientific paper, it is important to be able to understand the research question, and to identify shortcomings in the methods used to generate the results; doing so might be useful for clinical practice or further research. Thoma and Eaves1 provide guidance for novice plastic surgeons, who want to perform a meta-analysis on a specific subject, on how to improve their methodology and choose the right research question before starting a large-scale, time-consuming study. This would avoid the wasted effort associated with not asking an appropriate research question. As an example, they argue that our research question “What are the rates and potential predictive risk factors for complications in circumferential contouring of the lower trunk?” was not completely …

Published
2017

5. Are There Factors Predictive of Postoperative Complications in Circumferential Contouring of the Lower Trunk? A Meta-Analysis

Author

Antoine De Runz, Raphael Carloni, Christian Herlin, Florian Naudet, Nicolas Bertheuil, Paul Girard, Eric Watier, Benoit Chaput, Service de chirurgie plastique, reconstructive et esthétique [Rennes] = Cosmetic Reconstructive and Plastic surgery [Rennes], CHU Pontchaillou [Rennes], Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Rangueil, Department of Plastic and Craniofacial Pediatric Surgery, Hôpital Lapeyronie [Montpellier] (CHU), Médialab (Sciences Po) (Médialab), Sciences Po (Sciences Po), Microenvironnement et cancer (MiCa), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Etablissement français du sang [Rennes] (EFS Bretagne), STROMALab, Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Etablissement Français du Sang-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), médialab (Sciences Po) (médialab), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement Français du Sang-Centre National de la Recherche Scientifique (CNRS), Service de chirurgie plastique, reconstructive et esthétique, Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CHU Pontchaillou [Rennes]-Hôpital Sud, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), and Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement Français du Sang-Centre National de la Recherche Scientifique (CNRS)

Subjects
medicine.medical_specialty, massive-weight-loss, Breast surgery, medicine.medical_treatment, Belt lipectomy, bariatric surgery, [SDV.CAN]Life Sciences [q-bio]/Cancer, lower-body lift, Cosmetic Techniques, 030230 surgery, outcomes, Risk Assessment, autologous gluteal augmentation, law.invention, 03 medical and health sciences, 0302 clinical medicine, Hematoma, Postoperative Complications, Randomized controlled trial, Weight loss, law, Risk Factors, Weight Loss, medicine, Humans, consecutive abdominoplasties, risk-factors, business.industry, Torso, General Medicine, breast surgery, Plastic Surgery Procedures, medicine.disease, belt lipectomy, 3. Good health, Surgery, loss patient, Treatment Outcome, 030220 oncology & carcinogenesis, Meta-analysis, medicine.symptom, Complication, Risk assessment, business
Abstract

Background The massive weight loss patient may require a circumferential contouring of the lower trunk. Objectives To summarize the complication rates and explore the possibility of predictive risk factors for complications. Methods We performed a systematic review using the PubMed and Cochrane databases to identify published articles on the topic. Random effects meta-analyses and meta-regression were conducted to synthesize the data gathered. Results The analysis included 28 studies and 1380 patients. All but one were retrospective cohorts or case studies. Circumferential contouring of the lower trunk resulted in 37% [95%-CI 30%; 44%] overall complications; 17% [95%-CI 12%; 24%] wound dehiscences; 4% [95%-CI 3%; 5%] skin necrosis; 5% [95%-CI 3%; 9%] infections; 3% [95%-CI 2%; 4%] hematomas; 13% [95%-CI 9%; 18%] seromas; 12% [95%-CI 7%; 21%] scar irregularities; 3% [95%-CI 2%; 5%] thromboembolism; and 5% [95%-CI 3%; 8%] revisions for complications. Lower body lift-related techniques were associated with a higher rate of overall complications than belt lipectomy-related techniques ( P = .002). No difference in complication rate was shown when performing a gluteal augmentation with flap. Due to insufficient data reported in the studies, risk factors for postoperative complications could not be assessed. Conclusions The whole literature provides very low reliable information. Confusion factors could not be ruled out to explain the increased complications rate for the lower body lift compared to the belt lipectomy. This finding needs to be confirmed in randomized trials. Collaborative efforts must be made to improve the evidence level of our practices and to serve patients in an optimal way. Level of Evidence 3 ![Graphic][1] Therapeutic [1]: /embed/inline-graphic-1.gif

Published
2016
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