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This paper explores the university, industry and government (UIG) research and development (R&D) collaborations that academia in South African higher education institutions (HEIs) with clothing-related programmes engage in. In the research on which the paper is based, Fashion, Consumer Science, Textiles and Clothing Management academia were purposively sampled to gather data regarding the UIG R&D collaborations. Data collection was conducted through an online questionnaire. Descriptive statistics were employed to analyze data and present results in figures and graphs. Findings show that majority surveyed academia had never been involved in UIG R&D collaborations with any government levels, the clothing, textiles, leather and footwear (CTLF) industry or other clothing related organizations. The paper concludes that the ability of surveyed academia to produce 'relevant' new knowledge may be limited due to under developed UIG R&D collaborations. The likelihood of the surveyed clothing-related programmes producing graduates with 'relevant skills' for a changing world may also be negatively impacted. [ABSTRACT FROM AUTHOR]