1. Association of blood pressure with clinical outcomes in older adults with chronic kidney disease
- Author
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João Delgado, W. David Strain, David Melzer, Kirsty Bowman, Jane A. H. Masoli, and William Henley
- Subjects
Male ,Aging ,medicine.medical_specialty ,Population ,Severity of Illness Index ,older people ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Risk Factors ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Renal Insufficiency, Chronic ,education ,Stroke ,Aged ,Proportional Hazards Models ,Retrospective Studies ,Aged, 80 and over ,education.field_of_study ,Creatinine ,business.industry ,Medical record ,blood pressure ,Retrospective cohort study ,General Medicine ,medicine.disease ,cardiovascular outcomes ,Blood pressure ,Treatment Outcome ,chemistry ,Heart failure ,Hypertension ,Female ,Geriatrics and Gerontology ,business ,030217 neurology & neurosurgery ,chronic kidney disease ,Kidney disease ,Research Paper - Abstract
Background in chronic kidney disease (CKD), hypertension is associated with poor outcomes at ages 60. In the 70 plus group with SBPs 140–169 mmHg, there was no increase in mortality, versus SBP 130–139. Similarly, SBPs 140–169 mmHg were not associated with increased incident heart failure, stroke or myocardial infarctions. SBPs 150 mmHg. Results were little altered after excluding those with declining SBPs during 5 years before baseline, or for longer-term outcomes (5–10 years after baseline). Conclusions in older primary care patients, CKD3 or 4 was the dominant outcome predictor. SBP 140–169 mmHg having little additional predictive value
- Published
- 2018