1. Latest advances in aging research and drug discovery
- Author
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Daniela Bakula, Alex Zhavoronkov, Nir Barzilai, Anastasia Georgievskaya, Andrea Ablasser, Martin Immanuel Bittner, Alexander Tyshkovskiy, Martin Borch Jensen, Morten Scheibye-Knudsen, Ana Martin-Villalba, Unmesh Lal, Quentin Vanhaelen, Cornelis F. Calkhoven, Adriano Aguzzi, Jerome N. Feige, Alexey Moskalev, Andrei V. Gudkov, Danica Chen, Aubrey de Grey, Michael A. Petr, Ivan V. Ozerov, David C. Rubinsztein, Adam Antebi, Tyler Golato, Matt Kaeberlein, Thorsten Hoppe, Pekka Katajisto, Vadim N. Gladyshev, Brian K. Kennedy, Centre of Excellence in Stem Cell Metabolism, Helsinki Institute of Life Science HiLIFE, and Stem Cell Aging Leukemia and Lymphoma (SALL)
- Subjects
0301 basic medicine ,Artificial intelligence ,Aging ,Population ageing ,Drug Industry ,PROTEOSTASIS ,Psychological intervention ,translation ,Meeting Report ,Selective inhibition ,Business model ,Exhibition ,03 medical and health sciences ,0302 clinical medicine ,Drug Discovery ,Humans ,LONGEVITY ,Healthy aging ,Pharmaceutical industry ,selective-inhibition ,Drug discovery ,business.industry ,Research ,Opinion leadership ,Cell Biology ,artificial intelligence ,3. Good health ,030104 developmental biology ,Engineering ethics ,3111 Biomedicine ,metformin ,business ,030217 neurology & neurosurgery - Abstract
An increasing aging population poses a significant challenge to societies worldwide. A better understanding of the molecular, cellular, organ, tissue, physiological, psychological, and even sociological changes that occur with aging is needed in order to treat age-associated diseases. The field of aging research is rapidly expanding with multiple advances transpiring in many previously disconnected areas. Several major pharmaceutical, biotechnology, and consumer companies made aging research a priority and are building internal expertise, integrating aging research into traditional business models and exploring new go-to-market strategies. Many of these efforts are spearheaded by the latest advances in artificial intelligence, namely deep learning, including generative and reinforcement learning. To facilitate these trends, the Center for Healthy Aging at the University of Copenhagen and Insilico Medicine are building a community of Key Opinion Leaders (KOLs) in these areas and launched the annual conference series titled "Aging Research and Drug Discovery (ARDD)" held in the capital of the pharmaceutical industry, Basel, Switzerland (www.agingpharma.org). This ARDD collection contains summaries from the 6th annual meeting that explored aging mechanisms and new interventions in age-associated diseases. The 7th annual ARDD exhibition will transpire 2nd-4th of September, 2020, in Basel.
- Published
- 2019
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