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Thus far, knowledge network research has been quantitative research, emphasizing that in limited industries, knowledge creation increasingly strengthens through geographical proximity or institutional connections. Although it has been suggested that knowledge networks should be researched using dynamic rather than static methods, the dynamic process of knowledge networks according to spatiotemporal changes has not been sufficiently researched. This paper uses the Chinese wine industry case to conduct related research. The results show that, first of all, wine-related knowledge creation activities were carried out in the big cities that formed the early market in the mid-2000s, and the geographical conditions in which the spatial scope was expanded were in the places that gradually developed over time. Second, although the spatial scope of knowledge creation activities is expanding with the active participation of private enterprise networks, private enterprises and the overall knowledge creation process are relatively isolated. Finally, in terms of the process of knowledge creation related to wine, in the development of regional linkages organizations relate to the knowledge providers who provide the required information, and have little to do with the geographically close knowledge providers. [ABSTRACT FROM AUTHOR]