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In this paper, we prove several new integral inequalities for the k-Hilfer fractional derivative operator, which is a fractional calculus operator. As a result, we have a whole new set of fractional integral inequalities. For the generalized fractional derivative, we also use Young's inequality to find new forms of inequalities. Such conclusions for this novel and generalized fractional derivative are extremely useful and valuable in the domains of differential equations and fractional differential calculus, both of which have a strong connections to real-world situations. These findings may stimulate additional research in a variety of fields of pure and applied sciences.

In this article, we develop a new class of trapezium-type inequalities up to twice differentiable h-convex mappings for fractional integrals of Riemann-type. We conclude numerous existing results in literature from our general inequalities. Based on our consequences, we will obtain some quadrature formulas as applications.

This article is concerned to develop a novel generalized class of fractional impulsive delay differential equations. These equations are defined using newly discovered generalized conformable fractional operators which unify various previously-defined operators into a single form. The successive approximation method is employed and a sufficient criterion for the existence and uniqueness of the solution is developed. For the sake of illustration, three examples are provided at the end of the main results.

In this paper, we at first develop a generalized integral identity by associating Riemann-Liouville (RL) fractional integral of a function concerning another function. By using this identity estimates for various convexities are accomplish which are fractional integral inequalities. From our results, we obtained bounds of known fractional results which are discussed in detail. As applications of the derived results, we obtain the mid-point-type inequalities. These outcomes might be helpful in the investigation of the uniqueness of partial differential equations and fractional boundary value problems.

In this article, we investigate existence and the exact solutions of the extended Fisher-Kolmogorov (EFK) equation. This equation is used in the population growth dynamics and wave propagation. The fourth-order term in this model describes the phase transitions near critical points which are also known as Lipschitz points. He's variational method is adopted to construct the soliton solutions as well as the periodic wave solutions successfully for the extended (higher-order) EFK equation. This approach is simple and has the greatest advantages because it can reduce the order of our equation and make the equation more simple. So, the results that are obtained by this approach are very simple and straightforward. The graphics behavior of these solutions are also sketched in 3D, 2D, and corresponding contour representations by the different choices of parameters.

In this article, we have introduced the diarrhea disease dynamics in a varying population. For this purpose, a classical model of the viral disease is converted into the fractional-order model by using Atangana-Baleanu fractional-order derivatives in the Caputo sense. The existence and uniqueness of the solutions are investigated by using the contraction mapping principle. Two types of equilibrium points i.e., disease-free and endemic equilibrium are also worked out. The important parameters and the basic reproduction number are also described. Some standard results are established to prove that the disease-free equilibrium state is locally and globally asymptotically stable for the underlying continuous system. It is also shown that the system is locally asymptotically stable at the endemic equilibrium point. The current model is solved by the Mittag-Leffler kernel. The study is closed with constraints on the basic reproduction number $ R_{0} $ and some concluding remarks.

In the recent article, a reaction-advection-diffusion model of the hepatitis-B virus (HBV) is studied. Existence and uniqueness of the optimal solution for the proposed model in function spaces is analyzed. The advection and diffusion terms make the model more generic than the simple model. So, the numerical investigation plays a vital role to understand the behavior of the solutions. To find the existence and uniqueness of the optimal solutions, a closed and convex subset (closed ball) of the Banach space is considered. The explicit estimates regarding the solution of the system for the admissible auxiliary data is computed. On the other hand, for the numerical approximation of the solution, an elegant numerical technique is devised to find the approximate solutions. After constructing the discrete model, some fundamental properties must necessarily be possessed by the proposed numerical scheme. For instance, consistency, stability, and positivity of the solutions. These properties are carefully studied in the current article. To prove the positivity of the proposed scheme, M-matrix theory is used. All the above mentioned properties are verified by sketching the graph via simulations. Furthermore, these plots are helpful to understand the true behavior of the solutions. For this purpose, a fruitful discussion is included about the simulations to justify our results.