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Accelerator Mass Spectrometry (AMS), initiated in late 1970s at McMaster university based on the accelerator and detector technique, has long been applied in the studies on archaeology, geology, and cosmology, as a powerful tool for isotope dating. The advantages of AMS in the analysis of rare nuclides by direct counting of the atoms, small sample size and relatively free from the interferences of molecular ions have been well documented. This paper emphasizes that AMS can not only be used for archaeology, geology, environment, biology and so on, but also served as a unique tool for nuclear physics research. In this paper, the determination of the half-lives of {sup 79}Se, the measurements of the cross-sections of {sup 93}Nb(n,2n){sup 92g}Nb and {sup 238}U(n,3n){sup 236}U reactions, the detection and determination of ultratrace impurities in neutrino detector materials, and the measurement of the fission product nuclide {sup 126}Sn, are to be introduced, as some of examples of AMS applications in nuclear research conducted in AMS lab of China Institute of Atomic Energy. Searching for superheavy nuclides by using AMS is being planned.