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1. An Ethical Argument for Ending Human Trials of Amyloid-Lowering Therapies in Alzheimer's Disease

Author

Karl Herrup, Alberto Espay, and Timothy Daly

Subjects
General Neuroscience
Abstract

Given the past two decades of over 40 failed trials of amyloid-lowering therapies in Alzheimer's Disease (AD), many of which succeeded in lowering amyloid as designed, we present an ethical argument for emptying the drug pipeline of tests of amyloid-lowering agents so as to end the historical dominance of the amyloid-reducing therapeutic approach in AD.

Published
2022

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