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4School of Medicine, China Medical University, Taichung, Taiwan. eoplasms with perivascular epithelioid cell differentiation (PEComas) are mesenchymal tumors composed of distinctive perivascular epithelioid cells [1]. PEComas can be found in various organs [2]. Angiomyolipoma (AML) is one of the PEComa family, which is benign in entity and the most common mesenchymal tumor of the kidney [1, 2]. Malignant AML is extremely rare and most of them are found to be epithelioid AML histopathologically [1, 3]. Imaging features of multifoci AMLs have rarely been reported in the literature [3–5]. We describe the case of a 60-year-old woman with a huge left renal AML who subsequently developed multiple malignant AMLs in the lungs, lymph nodes, mediastinum, and cervical and thoracic spine. The imaging and pathologic features are presented. The pathogenesis of multicentric AMLs is discussed.

The objective of our study was to evaluate the efficacy of hypertonic saline for the treatment of liver tumors.Thirty New Zealand white rabbits inoculated with VX2 carcinoma in the liver were included in this experiment. These animals were divided into two groups: one for the evaluation of survival time (n = 20) and the other, for tumor size (n = 10). Each group was divided further into control and treatment subgroups. Hypertonic saline was injected directly into the liver tumor of the treatment group under CT guidance 10 days after inoculation. The liver tumor in the control group was injected with normal saline. The group for evaluation of tumor size was sacrificed 14 days later. The other group was raised until they died.The survival time of the rabbits in the treatment group (38.1 +/- 2.3 days) was significantly longer (p0.001) than that of the untreated group (29.9 +/- 2.9 days). For tumor size, the difference between the treatment group (8.04 +/- 2.46 cm(2)) and the control group (11.08 +/- 2.52 cm(2)) was also significant (p0.05).Hypertonic saline injection had the effect of controlling the growth of VX2 carcinoma cells and extending the life of rabbits. It deserves further investigation.

OBJECTIVE: This study investigated the findings revealed by dynamic helical CT of proximal arterioportal shunting associated with hepatocellular carcinoma. We also evaluated the diagnostic capability of this imaging technique to reveal the mass in patients with hepatocellular carcinoma. CONCLUSION: On dynamic helical CT, proximal arterioportal shunting altered liver perfusion and tumor enhancement. Heterogeneous enhancement of liver parenchyma and decreased enhancement of hepatomas diminished diagnostic capability on the arterial dominant phase image. However, with the addition of imaging in the arterial portal phase, lesion conspicuity improved.