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Your search keyword '"Lin, Cailu"' showing total 2 results
2 results on '"Lin, Cailu"'

2. Long‐term aspirin desensitization has mucosal cytokine features of immune tolerance.

Author

Kohanski, Michael A., Qatanani, Anas, Lin, Cailu, Tan, Li Hui, Chang, Jeremy, Corr, Andrew, Herzberg, Sabrina, Adappa, Nithin D., Palmer, James N., Reed, Danielle R., Bosso, John V., and Cohen, Noam A.

Subjects
IMMUNOLOGICAL tolerance, ALLERGY desensitization, NASAL polyps, ASPIRIN, CYTOKINES, TH2 cells, TUMOR necrosis factors
Abstract

This article discusses the long-term effects of aspirin desensitization on the inflammatory response in patients with aspirin-exacerbated respiratory disease (AERD). The study found that after long-term aspirin desensitization, there were significant increases in interferon-gamma (IFN-γ) and interleukin-10 (IL-10), suggesting a shift in the inflammatory response. These cytokines are associated with immune tolerance and may play a role in the mechanism of aspirin desensitization. However, the specific cells producing these cytokines and the role of lipid mediators in aspirin desensitization were not addressed in this study. Further research is needed to understand the cellular context and mechanisms associated with these cytokine shifts. [Extracted from the article]

Published
2024
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