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1. The relationship between objective physical activity and change in cognitive function

Author

Kelsey R. Sewell, Stephanie R. Rainey‐Smith, Jeremiah Peiffer, Hamid R. Sohrabi, Kevin Taddei, David Ames, Paul Maruff, Colin L. Masters, Christopher C. Rowe, Ralph N. Martins, Kirk I. Erickson, and Belinda M. Brown

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2023

2. Plasma glial fibrillary acidic protein is associated with reactive astrogliosis assessed via 18 F‐SMBT‐1 PET

Author

Pratishtha Chatterjee, Vincent Dore, Steve Pedrini, Natasha Krishnadas, Rohith N Thota, Pierrick Bourgeat, Stephanie Rainey‐Smith, Samantha C Burnham, Christopher Fowler, Kevin Taddei, Rachel S Mulligan, David Ames, Colin L. Masters, Jurgen Fripp, Christopher Rowe, Ralph N Martins, and Victor L Villemagne

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2022

3. Objectively measured physical activity and cognition in cognitively normal older adults: A longitudinal analysis of the Australian Imaging Biomarkers and Lifestyle (AIBL) study

Author

Kelsey R Sewell, Stephanie Rainey‐Smith, Victor L Villemagne, Jeremiah J Peiffer, Hamid R Sohrabi, Kevin Taddei, David Ames, Paul Maruff, Simon M Laws, Colin L. Masters, Christopher Rowe, Ralph N Martins, Kirk I. Erickson, and Belinda M Brown

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2022

4. How lifestyle shapes the brain: Associations between physical activity, sleep, beta‐amyloid and cognitive function in older adults

Author

Kelsey R Sewell, Stephanie R Rainey‐Smith, Victor LL Villemagne, Jeremiah J Peiffer, Hamid R Sohrabi, Kevin Taddei, David Ames, Paul T Maruff, Simon M Laws, Colin L Masters, Christopher C Rowe, Ralph N Martins, Kirk I. Erickson, and Belinda M Brown

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2021

5. Lipidomic signatures for APOE genotypes provides new insights about mechanisms of resilience in Alzheimer’s disease

Author

Tingting Wang, Kevin Huynh, Corey Giles, Wei Ling Florence Lim, Thy Duong, Natalie A. Mellett, Alexander Smith, Gavriel Olshansky, Brian G. Drew, Gemma Cadby, Phillip E. Melton, Joseph Hung, John Beilby, Gerald F. Watts, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Ralph N. Martins, Eric Moses, Rima F. Kaddurah‐Daouk, and Peter J Meikle

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2021

6. Identification of concordant plasma lipid signatures in Alzheimer’s disease: Validation between two independent studies of Alzheimer’s disease

Author

Adam Alexander T. Smith, Kaushala S. Jayawardana, Matthias Arnold, Ashley I. Bush, Gavriel Olshansky, Xianlin Han, David Ames, Ian Martins, Agus Salim, Simon M. Laws, Kevin Huynh, Victor L. Villemagne, Corey Giles, Christopher C. Rowe, Kwangsik Nho, Rebecca Baillie, Andrew J. Saykin, Rima Kaddurah-Daouk, Brian G. Drew, Wei Ling Florence Lim, Pratishtha Chatterjee, Colin L. Masters, Ralph N. Martins, Natalie A. Mellett, and Peter J. Meikle

Subjects
Epidemiology, business.industry, Health Policy, Computational biology, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Lipidomics, Plasma lipids, Medicine, Identification (biology), Neurology (clinical), Geriatrics and Gerontology, business
Published
2020

7. Improved centiloid robustness using non‐negative matrix factorization

Author

Christopher C. Rowe, Victor L. Villemagne, Vincent Dore, David Ames, Jurgen Fripp, Pierrick Bourgeat, Ralph N. Martins, and Colin L. Masters

Subjects
Epidemiology, Computer science, business.industry, Health Policy, Disease progression, Pattern recognition, Tracking (particle physics), Non-negative matrix factorization, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Neuroimaging, Robustness (computer science), Neurology (clinical), Artificial intelligence, Geriatrics and Gerontology, business
Published
2020

8. Elevated levels of synaptic protein GAP‐43 associate with brain tauopathy, atrophy and cognition in Alzheimer’s disease

Author

Petra L. Graham, Ashley I. Bush, Kaj Blennow, Colin L. Masters, Veer Bala Gupta, Christopher Fowler, Qiao-Xin Li, Henrik Zetterberg, Steven J. Collins, Victor L. Villemagne, Pierrick Bourgeat, Kunal Dhiman, David Ames, Ralph N. Martins, Dhamidhu Eratne, and Christopher C. Rowe

Subjects
Epidemiology, business.industry, Health Policy, Alzheimer's disease biomarkers, Cognition, medicine.disease, Synaptic protein, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Atrophy, Developmental Neuroscience, Neuroimaging, medicine, Neurology (clinical), Tauopathy, Geriatrics and Gerontology, Differential diagnosis, business, Neuroscience
Published
2020

9. Deficits in learning are greater than memory dysfunction in preclinical Alzheimer’s disease

Author

Andrea Mills, David Ames, Jenalle E. Baker, Stephanie R. Rainey-Smith, Loren Bruns, Colin L. Masters, Jurgen Fripp, Christopher Fowler, Yen Ying Lim, and Paul Maruff

Subjects
Memory Dysfunction, Epidemiology, business.industry, Health Policy, Neuropsychology, Cognition, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Clinical psychology
Published
2020

10. Genome‐wide study of the human lipidome and links to Alzheimer’s disease risk

Author

Natalie A. Mellett, Matthias Arnold, Peter J. Meikle, Rebecca Baillie, Adam Alexander T. Smith, Eric Moses, Rima Kaddurah-Daouk, Corey Giles, Gavriel Olshansky, Andrew J. Saykin, David Ames, Victor L. Villemagne, Ian Martins, Ashley I. Bush, Kevin Huynh, Xianlin Han, Michael Inouye, Gemma Cadby, Gabi Kastenmüller, Anh Nguyen, Christopher C. Rowe, Kwangsik Nho, Simon M. Laws, Colin L. Masters, Ralph N. Martins, and Pratishtha Chatterjee

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Disease risk, Neurology (clinical), Computational biology, Geriatrics and Gerontology, Lipidome, Biology, Genome
Published
2020

11. Comparison of peer mentoring versus peer support in a 6‐month home‐based physical activity program for inactive older adults at risk of Alzheimer’s disease: Experiences from the INDIGO trial

Author

Elizabeth V. Cyarto, Jennifer Southam, Nicola T. Lautenschlager, Kay L. Cox, Christopher Etherton-Beer, Dina LoGiudice, Danny Liew, Linda Clare, Osvaldo P. Almeida, Kathryn A. Ellis, David Ames, and Leon Flicker

Subjects
Gerontology, Epidemiology, Health Policy, Physical activity, Disease, Peer support, Home based, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Peer mentoring, Neurology (clinical), Geriatrics and Gerontology, Psychology
Published
2020

12. The association between mesial temporal tau with age, cognition and neocortical tau in Aβ cognitively unimpaired individuals using MK‐6240

Author

David Ames, Pierrick Bourgeat, Victor L. Villemagne, Anita M.Y. Goh, Colin L. Masters, Vincent Dore, Natasha Krishnadas, Kun Huang, Ralph N. Martins, Jurgen Fripp, Samantha C. Burnham, Paul Maruff, Colin Groot, and Christopher C. Rowe

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Cognition, Neurology (clinical), Geriatrics and Gerontology, Biology, Association (psychology), Neuroscience
Published
2020

13. P1‐142: PERIPHERAL INFLAMMATORY BURDEN BIOMARKERS MODULATE THE RISK FOR ALZHEIMER'S DISEASE THROUGH KEY AD‐RELATED SNPS

Author

Paul Maruff, James D. Doecke, Ralph N. Martins, David Ames, Christopher C. Rowe, Simon M. Laws, Stephanie R. Rainey-Smith, Tenielle Porter, Samantha L. Gardener, Colin L. Masters, and Olivier Salvado

Subjects
Epidemiology, business.industry, Health Policy, Single-nucleotide polymorphism, Disease, Bioinformatics, Peripheral, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Key (cryptography), Medicine, Neurology (clinical), Geriatrics and Gerontology, business
Published
2018

14. P2‐415: QUANTITATIVE NORMALISED SODIUM MRI SIGNAL INTENSITY IS NOT ASSOCIATED WITH AGE IN COGNITIVELY NORMAL OLDER ADULTS: A 3 TESLA STUDY

Author

Christopher Steward, Patricia Desmond, David Ames, Elizabeth V. Cyarto, Nicola T. Lautenschlager, Kathryn A. Ellis, Chris Kokkinos, Vijay K. Venkatraman, Kay L. Cox, Elaine Liu, Tie-Qiang Li, Brad Sutton, Bradford A. Moffat, and Scott C Kolbe

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, business.industry, Health Policy, Sodium MRI, Medicine, Neurology (clinical), Geriatrics and Gerontology, Signal intensity, business, Nuclear medicine
Published
2018

15. IC‐P‐008: VISUAL ASSESSMENT OF β‐AMYLOID PET SCAN IS IMPROVED BY CAPAIBL

Author

Victor L. Villemagne, Jurgen Fripp, John R. Hodges, Vincent Dore, Scott Williams, Claire E. Shepherd, Parnesh Raniga, Cristian E. Leyton, Colin L. Masters, Olivier Salvado, Ralph N. Martins, Christopher C. Rowe, Pierrick Bourgeat, Catriona MacLean, David Ames, Fairlie Hinton, Glenda M. Halliday, Sanka Amadoru, and Tia Cummins

Subjects
Pathology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, β amyloid, Visual assessment, medicine, Neurology (clinical), Geriatrics and Gerontology, business
Published
2018

16. O2‐15‐03: DIFFERENTIAL RISK FACTORS FOR PROGRESSION TO MCI/DEMENTIA BY AMYLOID‐BETA STATUS

Author

Yen Ying Lim, Christa Dang, Nawaf Yassi, Christopher C. Rowe, Colin L. Masters, Victor L. Villemagne, Paul Maruff, Martha Hickey, Karra Harrington, and David Ames

Subjects
Oncology, medicine.medical_specialty, biology, Epidemiology, Amyloid beta, business.industry, Health Policy, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, biology.protein, Dementia, Neurology (clinical), Geriatrics and Gerontology, business, Differential (mathematics)
Published
2018

17. P4‐112: VERBAL LEARNING AND BETA‐AMYLOID: REPEATED ADMINISTRATION OF THE INTERNATIONAL SHOPPING LIST TEST

Author

Victor L. Villemagne, Jenalle E. Baker, Paul Maruff, Peter J. Snyder, Robert H. Pietrzak, Christopher C. Rowe, David Ames, Yen Ying Lim, Judith Jaeger, and Colin L. Masters

Subjects
Amyloid, Epidemiology, business.industry, Health Policy, Verbal learning, Test (assessment), Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Beta (finance), Administration (government), Shopping list, Clinical psychology
Published
2018

18. P1‐405: VISUAL ASSESSMENT OF β‐AMYLOID PET SCAN IS IMPROVED BY CAPAIBL

Author

Vincent Dore, Pierrick Bourgeat, Tia L. Cummins, Parnesh Raniga, Scott Williams, Sanka Amadoru, Catriona MacLean, Fairlie Hinton, Claire Shepherd, Glenda M. Halliday, Cristian E. Leyton, John R. Hodges, David Ames, Ralph N. Martins, Colin L. Masters, Jurgen Fripp, Olivier Salvado, Victor L. Villemagne, and Christopher Rowe

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2018

19. P1‐440: INCREASED CEREBRAL BLOOD FLOW WITH INCREASED AMYLOID BURDEN IN PRECLINICAL AD

Author

Lifestyle (Aibl), David Ames, Jurgen Fripp, Olivier Salvado, Xiaoyun Liang, Alan Connelly, Fernando Calamante, Vincent Dore, Christopher C. Rowe, Pierrick Bourgeat, Victor L. Villemagne, Parnesh Raniga, Amir Fazlollahi, and Colin L. Masters

Subjects
Pathology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Cerebral blood flow, Medicine, Amyloid burden, Neurology (clinical), Geriatrics and Gerontology, business
Published
2018

20. O1‐04‐01: PRECLINICAL ALZHEIMER'S DISEASE IS ASSOCIATED WITH LEARNING IMPAIRMENTS OVER SIX DAYS: RESULTS FROM THE ONLINE REPEATED COGNITIVE ASSESSMENT (ORCA) STUDY

Author

Jenalle E. Baker, Victor L. Villemagne, David Ames, Loren Bruns, Yen Ying Lim, Paul Maruff, Jason Hassenstab, Stephanie R. Rainey-Smith, Colin L. Masters, Christopher C. Rowe, and Christopher Fowler

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Physical medicine and rehabilitation, Developmental Neuroscience, medicine, Neurology (clinical), Cognitive Assessment System, Geriatrics and Gerontology, business
Published
2018

21. O4‐06‐01: GENETIC VARIATION IN AQUAPORINS MODERATES THE RELATIONSHIP BETWEEN SLEEP AND BRAIN Aβ‐AMYLOID BURDEN

Author

Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Hamid R. Sohrabi, Colin L. Masters, Lidija Milicic, Paul Maruff, Olivier Salvado, Gavin Noel Mazzucchelli, Stephanie R. Rainey-Smith, Ralph N. Martins, Kevin Taddei, Michael Weinborn, Simon M. Laws, Belinda M. Brown, David Ames, and Romola S. Bucks

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Genetic variation, Aquaporin, Aβ amyloid, Neurology (clinical), Geriatrics and Gerontology, Biology, Sleep in non-human animals, Neuroscience
Published
2018

22. O4‐09‐01: COMPARISON OF THE NATURAL HISTORY OF NEOCORTICAL Aβ‐AMYLOID, HIPPOCAMPAL VOLUME AND PACC IN SPORADIC AD

Author

Christopher C. Rowe, Reisa A. Sperling, Vincent Dore, Pierrick Bourgeat, Olivier Salvado, Paul Maruff, Samantha C. Burnham, Victor L. Villemagne, Ralph N. Martins, Simon M. Laws, Colin L. Masters, David Ames, Greg Savage, and Charley Ann Budgeon

Subjects
Natural history, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Chemistry, Health Policy, Hippocampal volume, Aβ amyloid, Neurology (clinical), Geriatrics and Gerontology, Neuroscience
Published
2018

23. P1‐006: EXAMINING THE RESILIENCE OF SUPERAGERS: RISK OF CLINICAL PROGRESSION AND Aβ‐ASSOCIATED MEMORY DECLINE OVER 8 YEARS

Author

Karra Harrington, Martha Hickey, David Ames, Victor L. Villemagne, Yen Ying Lim, Christopher C. Rowe, Christa Dang, Nawaf Yassi, Colin L. Masters, and Paul Maruff

Subjects
Gerontology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, business.industry, Health Policy, Medicine, Neurology (clinical), Geriatrics and Gerontology, Resilience (network), business, Clinical progression
Published
2018

24. IC‐06‐01: QUANTITATIVE SODIUM MRI IS MORE SENSITIVE THAN VOLUMETRY FOR DIFFERENTIATING BETWEEN OLDER ADULTS WITH MILD COGNITIVE IMPAIRMENT AND THOSE WHO ARE COGNITIVELY NORMAL

Author

David Ames, Kay L. Cox, Elaine Liu, Nicola T. Lautenschlager, Scott C Kolbe, Christopher Steward, Vijay K. Venkatraman, Elizabeth V. Cyarto, Patricia Desmond, Kathryn A. Ellis, Chris Kokkinos, Tie-Qiang Li, Brad Sutton, and Bradford A. Moffat

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Audiology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Sodium MRI, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Cognitive impairment
Published
2018

25. P3‐470: PAIRED ASSOCIATE LEARNING DEFICITS ASSOCIATED WITH ELEVATED BETA‐AMYLOID IN COGNITIVELY NORMAL OLDER ADULTS

Author

Peter J. Snyder, Victor L. Villemagne, Robert H. Pietrzak, Christopher C. Rowe, Yen Ying Lim, Jenalle E. Baker, David Ames, Paul Maruff, Judith Jaeger, and Colin L. Masters

Subjects
medicine.medical_specialty, Amyloid, Epidemiology, business.industry, Health Policy, Paired associate learning, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Endocrinology, Developmental Neuroscience, Internal medicine, medicine, Neurology (clinical), Geriatrics and Gerontology, Beta (finance), business
Published
2018

26. P1‐636: DOES MENTOR‐SUPPORTED GOAL‐SETTING ENHANCE ADHERENCE TO A 6‐MONTH PHYSICAL ACTIVITY PROGRAM, IMPROVE PHYSICAL ACTIVITY AND FITNESS FOR INACTIVE OLDER ADULTS AT RISK OF ALZHEIMER'S DISEASE? THE INDIGO TRIAL

Author

Christopher Etherton-Beer, Kay L. Cox, Elizabeth V. Cyarto, Osvaldo P. Almeida, Dina LoGiudice, Linda Clare, Helman Alfonso, Kathryn A. Ellis, Danny Liew, Jennifer Southam, Nicola T. Lautenschlager, L. Flicker, and David Ames

Subjects
Gerontology, Epidemiology, business.industry, Health Policy, Physical activity, Disease, Indigo, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Goal setting
Published
2018

27. P3‐620: INCREASED PROTEIN AND FIBRE INTAKE IS ASSOCIATED WITH HIGHER PERFORMANCE IN THE AIBL PACC SCORE IN COGNITIVELY NORMAL ADULTS: AUSTRALIAN IMAGING, BIOMARKERS AND LIFESTYLE (AIBL) STUDY

Author

Victor L. Villemagne, Greg Savage, James D. Doecke, Paul Maruff, Colin L. Masters, Olivier Salvado, David Ames, Samantha C. Burnham, Warnakulasuriya M. A. D. B. Fernando, Michael Weinborn, Ralph N. Martins, Samantha L. Gardener, Biomarker Australian Imaging, Hamid R. Sohrabi, Stephanie R. Rainey-Smith, and Christopher C. Rowe

Subjects
Oncology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, medicine.medical_specialty, Developmental Neuroscience, Epidemiology, business.industry, Health Policy, Internal medicine, medicine, Neurology (clinical), Geriatrics and Gerontology, business
Published
2018

28. O3‐07‐06: IMPROVEMENTS IN SUBTHRESHOLD ANXIETY AND DEPRESSION SYMPTOMS IN OLDER, SEDENTARY ADULTS AT RISK OF ALZHEIMER'S DISEASE WHO ENGAGE IN A PHYSICAL ACTIVITY INTERVENTION

Author

Kay L. Cox, Danny Liew, Kathryn A. Ellis, Christopher Etherton-Beer, David Ames, Nicola T. Lautenschlager, Dina LoGiudice, Emily You, Linda Clare, Osvaldo P. Almeida, Helman Alfonso, Elizabeth V. Cyarto, and L. Flicker

Subjects
Epidemiology, business.industry, Subthreshold conduction, Health Policy, Physical activity, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Intervention (counseling), Medicine, Anxiety, Neurology (clinical), Geriatrics and Gerontology, medicine.symptom, business, Depression (differential diagnoses), Clinical psychology
Published
2018

29. P2‐634: CHANGES IN PHYSICAL ACTIVITY, GOAL‐SETTING SATISFACTION AND PERFORMANCE WITH A SIX‐MONTH, HOME‐BASED, PHYSICAL ACTIVITY PROGRAM IN INACTIVE OLDER ADULTS AT RISK OF ALZHEIMER'S DISEASE: THE INDIGO TRIAL

Author

Kay L. Cox, Danny Liew, Christopher Etherton-Beer, David Ames, Helman Alfonso, Linda Clare, Kathryn A. Ellis, L. Flicker, Dina LoGiudice, Jennifer Southam, Nicola T. Lautenschlager, Elizabeth V. Cyarto, and Osvaldo P. Almeida

Subjects
Gerontology, Epidemiology, business.industry, Health Policy, Physical activity, Disease, Home based, Indigo, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Goal setting
Published
2018

30. F3-04-03: STAKEHOLDER PERSPECTIVES ON HOW THE HOME CARE SECTOR CAN SUPPORT PEOPLE TO LIVE WELL WITH DEMENTIA

Author

Frances Batchelor, Colleen Doyle, Philip Clarke, Samantha M Loi, Lee-Fay Low, Jason Burton, Anita M.Y. Goh, Constantine G. Lyketsos, Steven Savvas, Ellen Gaffy, Luke Gahan, Gill Livingston, Margaret Winbolt, David Ames, Brendan Hallam, Briony Dow, Samuel C Scherer, Meg Polacsek, Claudia Cooper, Sue Malta, and Anita Panayiotou

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Nursing, Epidemiology, Health Policy, Stakeholder, medicine, Dementia, Neurology (clinical), Business, Geriatrics and Gerontology, medicine.disease
Published
2019

31. P2-581: THE SUPPORT PERSON'S PREFERENCES AND PERSPECTIVES OF PHYSICAL ACTIVITY FOR OLDER ADULTS WITH COGNITIVE IMPAIRMENT

Author

Nicola T. Lautenschlager, David Ames, Terence W.H. Chong, Kay L. Cox, Stephanie R. Rainey-Smith, Karra Harrington, Emily You, and Kathryn A. Ellis

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Physical activity, Support person, Neurology (clinical), Geriatrics and Gerontology, Cognitive impairment, Psychology, Clinical psychology
Published
2019

32. IC-P-167: AUTOMATED REPORTING OF TAU PET QUANTIFICATION ON BRAIN SURFACE

Author

Victor L. Villemagne, David Ames, Samantha C. Burnham, Jurgen Fripp, Vincent Dore, Pierrick Bourgeat, Ralph N. Martins, Christopher C. Rowe, Colin L. Masters, and Olivier Salvado

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Chemistry, Health Policy, Neurology (clinical), Brain surface, Geriatrics and Gerontology, Biomedical engineering
Published
2019

33. [IC‐P‐158]: IMPLEMENTING THE CENTILOID TRANSFORMATION FOR 18 F‐FLORBETABEN AND 18 F‐NAV4694 USING CAPAIBL

Author

Jurgen Fripp, Pierrick Bourgeat, David Ames, Colin L. Masters, Vincent Dore, Olivier Salvado, Victor L. Villemagne, and Christopher C. Rowe

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Pure mathematics, Transformation (function), Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology, Florbetaben, Mathematics
Published
2017

34. [P4–499]: REFINING THE NATURAL HISTORY OF GLOBAL AND REGIONAL Aβ‐AMYLOID DEPOSITION IN SPORADIC ALZHEIMER's DISEASE

Author

Pierrick Bourgeat, Stephanie R. Rainey-Smith, Olivier Salvado, Greg Savage, Ralph N. Martins, Vincent Dore, Christopher C. Rowe, Paul Maruff, Colin L. Masters, Samantha C. Burnham, Simon M. Laws, Victor L. Villemagne, David Ames, and Belinda M. Brown

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Chemistry, Refining, Health Policy, Environmental chemistry, Aβ amyloid, Neurology (clinical), Geriatrics and Gerontology, Deposition (chemistry)
Published
2017

35. [O4–04–06]: VASCULAR RISK MEASURES AND LONGITUDINAL Aβ ACCUMULATION: RESULTS FROM THE AIBL STUDY OF AGEING

Author

Victor L. Villemagne, Paul Yates, Christopher C. Rowe, David Ames, Olivier Salvado, Ralph N. Martins, Samantha C. Burnham, Stephanie R. Rainey-Smith, Colin L. Masters, and Vincent Dore

Subjects
Oncology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Vascular risk, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Ageing, Internal medicine, medicine, Neurology (clinical), Geriatrics and Gerontology, business
Published
2017

36. [P2–389]: LONGITUDINAL ASSESSMENT OF Aβ ACCUMULATION WITH FLUTEMETAMOL

Author

Christopher C. Rowe, David Ames, Pierrick Bourgeat, Olivier Salvado, Vincent Dore, Victor L. Villemagne, Colin L. Masters, and Robert W. Williams

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2017

37. [P4–561]: MEDITERRANEAN DIET ADHERENCE IS ASSOCIATED WITH ATTENUATED CORTICAL THINNING IN AN AUSTRALIAN STUDY OF AGEING

Author

Pierrick Bourgeat, Ralph N. Martins, Olivier Salvado, Stephanie R. Rainey-Smith, David Ames, Kaikai Shen, Colin L. Masters, Christopher C. Rowe, Kevin Taddei, and Samantha L. Gardener

Subjects
Pathology, medicine.medical_specialty, Mediterranean diet, Epidemiology, business.industry, Health Policy, Cortical thinning, Physiology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Ageing, Medicine, Neurology (clinical), Geriatrics and Gerontology, business
Published
2017

38. [F1–02–01]: DIAGNOSTIC AND PROGNOSTIC POWER OF FLUID AND NEUROIMAGING MARKERS OF PATHOLOGY AND NEURODEGENERATION: THE ALZHEIMER'S IMAGING, BIOMARKERS, AND LIFESTYLE (AIBL) STUDY OF AGEING EXPERIENCE

Author

Victor L. Villemagne, Christopher C. Rowe, Yen Ying Lim, Pierrick Bourgeat, Stephanie R. Rainey-Smith, Olivier Salvado, Veer Bala Gupta, Samantha C. Burnham, Qiao-Xin Li, Steven J. Collins, Simon M. Laws, Ralph N. Martins, Colin L. Masters, David Ames, Paul Maruff, Alan Rembach, Greg Savage, Vincent Dore, and James D. Doecke

Subjects
Pathology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Neurodegeneration, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Neuroimaging, Ageing, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Neuroscience
Published
2017

39. [P2–565]: CAN OLDER ADULTS AT RISK OF ALZHEIMER's DISEASE ADHERE TO A 24‐MONTH HOME‐BASED PHYSICAL ACTIVITY PROGRAM? THE AIBL ACTIVE–TRIAL

Author

Olivier Salvado, David Ames, Pramit M. Phal, Kay L. Cox, Matthew J. Sharman, Kathryn A. Ellis, Nicola T. Lautenschlager, Patricia Desmond, Cassandra Szoeke, and Elizabeth V. Cyarto

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Walk distance, Physical activity, Subjective memory, Disease, Home based, Memory problems, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Physical therapy, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Cognitive impairment, Cerebrovascular risk
Abstract

Background: Increased physical activity (PA) is associated with better cognitive function. We investigated whether individuals with memory problems and additional cerebrovascular risk factors (CVD) could increase PA in the short-term and maintain adherence to a PA program in the long-term. We also examined factors influencing PA adherence. Methods: The AIBL Active trial recruited participants with mild cognitive impairment (MCI) or subjective memory complaints (SMC) and at least 1 CVD risk factor from The Australian Imaging Biomarkers and Lifestyle Flagship Study of Aging (AIBL). They were randomly assigned to a control or PA group. The control group continued their usual PA throughout the study. The PA group was given a 24-month home-based program with a target of 150 minutes/week of moderate PA and a behavioral intervention. Scheduled group-specific phone calls (nｼ18) and newsletters (nｼ17) were administered to both groups over 24 months. The PA group recorded sessions in diaries and adherence was calculated from the number of sessions recorded expressed as the percentage of the sessions prescribed. At baseline, 6, 12 and 24 months participants completed fitness (6-minute walk distance); PA and PA self-efficacy (one痴 confidence to be physically active) questionnaires; cognitive and health assessments. Results: The adherence results for the PA group (nｼ55) comprising of 53% women are reported. At baseline 24% were defined as inactive; men were significantly older than women; 74.7(6SD 5.6) versus 70.1(4.8) years respectively. Five participants did not start the intervention. After 24 months 96% were still in the study. After 6 months mean PA adherence was 83.5% and declined over the trial with mean 24-month adherence being 75.2%. Age, gender and MCI did not significantly influence adherence. Higher baseline self-effi- cacy (p

Published
2017

40. [P3–243]: A MASS SPECTROMETRY‐BASED DISCOVERY AND REPLICATION OF A MULTI‐ANALYTE CLASSIFIER FOR NEOCORTICAL AMYLOID PATHOLOGY

Author

Veer Bala Gupta, Kathryn Gooze, David Ames, Victor L. Villemagne, Eugene Hone, Pratishtha Chatterjee, Dag Aarsland, Simon Lovestone, Colin L. Masters, Nicholas J. Ashton, Steve Pedrini, Alejo J. Nevado-Holgado, Steven Lynham, Christopher C. Rowe, Ralph N. Martins, Abdul Hye, Ashley I. Bush, and Malcolm Ward

Subjects
Amyloid pathology, Epidemiology, Health Policy, Biology, Mass spectrometry, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Replication (statistics), Neurology (clinical), Geriatrics and Gerontology, Classifier (UML), Neuroscience, Multi analyte
Published
2017

41. [P4–136]: IL‐10 AND IL‐12/23P40 ARE JOINTLY ASSOCIATED AS PREDICTORS OF Aβ‐AMYLOID LOAD IN A BROADER BLOOD‐BASED BIOMARKER PANEL

Author

Colin L. Masters, James D. Doecke, Eugene Hone, Veer Bala Gupta, Victor L. Villemagne, David Ames, Steve Pedrini, Ian James, Christopher C. Rowe, Ralph N. Martins, Ashley I. Bush, and Sid E. O'Bryant

Subjects
Epidemiology, Blood based biomarkers, business.industry, Health Policy, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Interleukin 10, Developmental Neuroscience, Immunology, Interleukin 12, Medicine, Aβ amyloid, Neurology (clinical), Geriatrics and Gerontology, business
Published
2017

42. [P1–607]: SELF‐REPORTED PHYSICAL ACTIVITY IS ASSOCIATED WITH TAU BURDEN AS MEASURED BY PET

Author

Kevin Taddei, Vincent Dore, Belinda M. Brown, Stephanie R. Rainey-Smith, Christopher C. Rowe, Victor L. Villemagne, Colin L. Masters, David Ames, Simon M. Laws, Jeremiah J. Peiffer, and Ralph N. Martins

Subjects
Oncology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Physical activity, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Nuclear medicine
Published
2017

43. [P2–086]: EDUCATION AND PHYSICAL ACTIVITY IN RELATION TO FRAILTY AND WHOLE‐BRAIN STRUCTURAL HEALTH IN ALZHEIMER'S DISEASE, MILD COGNITIVE IMPAIRMENT, AND NORMAL AGING: RESULTS FROM THE AUSTRALIAN IMAGING, BIOMARKERS AND LIFESTYLE FLAGSHIP STUDY OF AGEING (AIBL)

Author

Navjot Dhindsa, Ryan C.N. D'Arcy, Christopher C. Rowe, Stephanie R. Rainey-Smith, David Ames, Xiaowei Song, Kenneth Rockwood, Hui Guo, An Zeng, Belinda M. Brown, Ralph N. Martins, Olivier Salvado, and Colin L. Masters

Subjects
0301 basic medicine, Gerontology, Epidemiology, Health Policy, Physical activity, Normal aging, Disease, 03 medical and health sciences, Psychiatry and Mental health, Cellular and Molecular Neuroscience, 030104 developmental biology, Developmental Neuroscience, Ageing, Neurology (clinical), Geriatrics and Gerontology, Psychology, Cognitive impairment
Published
2017

44. [P3–325]: 18F‐AV1451 TAU QUANTIFICATION WITHOUT MRI

Author

Christopher C. Rowe, Jurgen Fripp, Olivier Salvado, David Ames, Pierrick Bourgeat, Victor L. Villemagne, Vincent Dore, and Colin L. Masters

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology
Published
2017

45. [O3–01–05]: THE SHORT‐ AND LONG‐TERM EFFECTS OF A 24‐MONTH HOME‐BASED PHYSICAL ACTIVITY PROGRAM ON PHYSICAL ACTIVITY LEVELS AND BODY COMPOSITION OF OLDER ADULTS AT RISK OF ALZHEIMER's DISEASE: THE AIBL ACTIVE TRIAL

Author

Kay L. Cox, Kathryn A. Ellis, Nicola T. Lautenschlager, Patricia Desmond, Pramit M. Phal, Matthew J. Sharman, Cassandra Szoeke, Olivier Salvado, David Ames, and Elizabeth V. Cyarto

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Physical activity, Disease, Home based, Term (time), Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Physical therapy, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Composition (language)
Published
2017

46. [O5–05–01]: COGNITIVE SUPER‐AGING VERSUS TYPICAL AGING IN COMMUNITY‐DWELLING OLDER ADULTS: LONGITUDINAL TRAJECTORIES IN GLOBAL CORTICAL THICKNESS OVER SIX YEARS

Author

Victor L. Villemagne, David Ames, Ralph N. Martins, Kaikai Shen, Belinda M. Brown, Christopher C. Rowe, Greg Savage, Kevin Taddei, Samantha L. Gardener, Michael Weinborn, Paul Maruff, Stephanie R. Rainey-Smith, James D. Doecke, Colin L. Masters, Olivier Salvado, and Hamid R. Sohrabi

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Context (language use), Cognition, Audiology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Cog, Developmental Neuroscience, Neuroimaging, Medicine, Neurology (clinical), Geriatrics and Gerontology, Left superior, business, Association (psychology), Episodic memory, Cognitive reserve
Abstract

Background It is common for older adults to experience decline in some cognitive functions with increasing age. Importantly, a subset, usually referred to as super-agers (SA; Rogalski, et al., 2013, J Cog Neurosc, 25: 29-36) live to an old age whilst continuing to maintain cognitive function at levels similar to demographically-matched peers at least 20-30 years their junior. The current study reports trajectories of change in cortical thickness on a well-defined group of SAs vs. typical agers (TA) followed longitudinally over six years in the Australian Imaging, Biomarkers & Lifestyle Study (AIBL) (Ellis et al., 2009, Int Psychogeriat, 2: 672-87). Methods Super-Agers were defined as individuals aged 60+ who scored in the normative range for individuals aged 30 – 44 on the CVLT-II, a test of verbal episodic memory, at baseline and two consecutive time-points 18 months apart. SAs additionally must have performed in the unimpaired range in all other cognitive domains, as compared to same-aged peers. Typical agers must have scored within the normal range on all cognitive measures compared with same-aged peers. This report describes data from 21 SAs and 24 TAs. The TAs were chosen from a larger group matched on age, education and gender to the SA group. All participants completed brain magnetic resonance imaging every 18 months for six years. We conducted multiple linear mixed models analyses to assess the association between preservation of cortical thickness in SAs and TAs. Results From 34 regions of interest identified as potentially differentiating SAs from TAs from previous neuroimaging studies, our results were consistent in finding greater cortical thinning amongst TAs in 20 of these regions (p-values ranging between ≤ .000 and .047), with an additional five regions at trend level (p-values ranging between ≥ .05 and .073). Using false discovery rates, we found significantly preserved thickness in three regions not previously reported including left superior parietal gyrus, left precuneus, and left paracentral lobule. Conclusions SAs and TAs displayed similar cortical thickness at baseline (p >.40), but showed different trajectories over time. The findings will be discussed in the context of current models of cognitive and brain reserve.

Published
2017

47. [P3–224]: THE INFLUENCE OF LOW‐DENSITY LIPOPROTEINS ON NEOCORTICAL AMYLOID LOAD IN THE AUSTRALIAN IMAGING BIOMARKER AND LIFESTYLE STUDY

Author

Christopher C. Rowe, Ralph N. Martins, Eugene Hone, Simon M. Laws, David Ames, Veer Bala Gupta, Alyce Russell, Victor L. Villemagne, Colin L. Masters, and Steve Pedrini

Subjects
Pathology, medicine.medical_specialty, Amyloid, Imaging biomarker, Epidemiology, Health Policy, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, medicine, Low density, Neurology (clinical), Geriatrics and Gerontology, Psychology, Neuroscience
Published
2017

48. [P3–462]: CONSIDERATION OF PRECLINICAL AD FROM THE PERSPECTIVE OF NORMAL AGING: AMYLOID‐β RELATED CHANGES IN FLUID AND CRYSTALLIZED INTELLIGENCE IN A ROBUST SAMPLE OF HEALTHY OLDER ADULTS

Author

Victor L. Villemagne, Adrian Schembri, Yen Ying Lim, Paul Maruff, Christopher C. Rowe, David Ames, Colin L. Masters, Stephanie R. Rainey-Smith, Olivier Salvado, and Karra Harrington

Subjects
Amyloid β, Epidemiology, Health Policy, Fluid and crystallized intelligence, Perspective (graphical), Sample (statistics), Normal aging, Developmental psychology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology (clinical), Geriatrics and Gerontology, Psychology
Published
2017

49. [P1–444]: QUANTITATIVE SUSCEPTIBILITY MAPPING OF THE HIPPOCAMPUS PREDICTS HIPPOCAMPAL ATROPHY IN Aβ+ ELDERLY CONTROLS AND ALZHEIMER's DISEASE PATIENTS

Author

David Ames, Jurgen Fripp, Scott Ayton, Parnesh Raniga, Christopher C. Rowe, Vincent Dore, Victor L. Villemagne, Ibrahima Diouf, Amanda Ng, Amir Fazlollahi, Ashley I. Bush, Olivier Salvado, Colin L. Masters, and Pierrick Bourgeat

Subjects
Pathology, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, 05 social sciences, Hippocampus, Quantitative susceptibility mapping, Disease, 050105 experimental psychology, Hippocampal atrophy, 03 medical and health sciences, Psychiatry and Mental health, Cellular and Molecular Neuroscience, 0302 clinical medicine, Developmental Neuroscience, medicine, 0501 psychology and cognitive sciences, Neurology (clinical), Geriatrics and Gerontology, business, 030217 neurology & neurosurgery
Published
2017

50. P4-485: SPON1 IS ASSOCIATED WITH Aβ-AMYLOID AND APOE ε4 RELATED COGNITIVE DECLINE IN COGNITIVELY NORMAL ADULTS

Author

Paul Maruff, Christopher C. Rowe, Victor L. Villemagne, Olivier Salvado, Tenielle Porter, David Groth, Samantha C. Burnham, Michael Weinborn, Colin L. Masters, Greg Savage, Simon M. Laws, Madeline Peretti, David Ames, Giuseppe Verdile, Lidija Milicic, Hamid R. Sohrabi, Ralph N. Martins, Stephanie R. Rainey-Smith, and Yen Ying Lim

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Endocrinology, Developmental Neuroscience, Internal medicine, Medicine, Aβ amyloid, Neurology (clinical), Geriatrics and Gerontology, Cognitive decline, business
Published
2019

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