1. Electromechanical dysfunction of the left atrium associated with interatrial block
- Author
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Sanjeev B. Goyal and David H. Spodick
- Subjects
Heart Failure ,medicine.medical_specialty ,Ejection fraction ,Heart block ,business.industry ,Stroke Volume ,Atrial fibrillation ,Interatrial Block ,Stroke volume ,medicine.disease ,Heart Block ,Atrial natriuretic peptide ,Echocardiography ,Risk Factors ,Heart failure ,Internal medicine ,Atrial Fibrillation ,medicine ,Cardiology ,Humans ,Heart Atria ,Thrombus ,Cardiology and Cardiovascular Medicine ,business - Abstract
Objectives Our purpose was to determine the effect of interatrial block (IAB, P-wave duration ≥120 ms) on left atrial (LA) dynamics. IAB is associated with LA enlargement (LAE). LA dysfunction is associated with decreased left ventricular filling, a propensity for LA appendage thrombus formation, and reduced atrial natriuretic peptide levels. We evaluated LA function in patients with and without IAB matched for LA size. Methods Echocardiograms with LA enlargement were analyzed. Twenty-four patients had IAB, and 16 patients without IAB formed the control group. LA volumes, A-wave acceleration times (At), LA stroke volume (LASV), ejection fraction (LAEF), and kinetic energy (LAKE) were calculated. Results The control group and patients with IAB had comparable maximal LA volume and diameter (P >.05). Patients with IAB had significantly longer At (115 ± 39 ms vs 83 ± 24 ms, P
- Published
- 2001
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