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Start Over Author "Anthony Picone" Journal american journal of clinical oncology
1 results on '"Anthony Picone"'

1. Prior Treatment for Non-small Cell Lung Cancer Is Associated With Improved Survival in Patients who Undergo Definitive Stereotactic Body Radiation Therapy for a Subsequent Lung Malignancy: A Retrospective Multivariate and Matched Pair Analysis

Author

Elisabeth U. Dexter, Sung Jun Ma, Anthony Picone, Simon Fung-Kee-Fung, Todd L. Demmy, Sai Yendamuri, Mark K. Farrugia, Chukwumere Nwogu, Jorge A. Gomez-Suescun, Mark Hennon, and Anurag K. Singh

Subjects
Oncology, Male, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Matched-Pair Analysis, Kaplan-Meier Estimate, Radiosurgery, Disease-Free Survival, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Carcinoma, Non-Small-Cell Lung, medicine, Humans, 030212 general & internal medicine, Lung cancer, Survival analysis, Aged, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, Lung, Performance status, Proportional hazards model, business.industry, Hazard ratio, medicine.disease, Radiation therapy, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cohort, Multivariate Analysis, Female, Dose Fractionation, Radiation, business
Abstract

BACKGROUND Despite occurring commonly, the prognoses of second early-stage non-small cell lung cancers (NSCLC) are not well known. METHODS The authors retrospectively reviewed the charts of inoperable patients who underwent thoracic stereotactic body radiation therapy (SBRT) from February 2007 to April 2019. Those with previous small cell lung cancers or SBRT treatments for tumors other than NSCLC were excluded. Multivariate Cox regression and a matched pair cohort analyses evaluated the prognoses of patients undergoing definitive SBRT for a new second primary. RESULTS Of 438 patients who underwent definitive SBRT for NSCLC, 84 had previously treated NSCLC. Univariate log-rank tests identified gender, Karnofksy performance status (KPS), prior lung cancer, anticoagulation use, and history of heart disease to correlate with overall survival (OS) (P

Published
2020

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