1. Lymphomatoid Papulosis With a Unique T Follicular Helper-Like Phenotype.
- Author
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Tran J, Duvic M, and Torres-Cabala CA
- Subjects
- Clobetasol therapeutic use, Glucocorticoids therapeutic use, Humans, Lymphomatoid Papulosis drug therapy, Male, Middle Aged, Neoplasms, Multiple Primary drug therapy, Phenotype, Skin Neoplasms drug therapy, Lymphomatoid Papulosis pathology, Neoplasms, Multiple Primary pathology, Skin Neoplasms pathology, T Follicular Helper Cells pathology
- Abstract
Lymphomatoid papulosis (LyP) is a benign skin condition that typically presents with grouped or scattered lesions on the body that self-resolve within weeks or months of onset. LyP belongs to the group of CD30-positive lymphoproliferative disorders. Several histological variants of LyP exist, and the histological features of LyP can overlap with other lymphoproliferative disorders; therefore, both histological and clinical correlations are needed for a proper diagnosis of LyP. We report an unusual case of LyP displaying a T follicular helper cell-like phenotype and histopathologically resembling the primary cutaneous CD4-positive small-sized to medium-sized T-cell lymphoproliferative disorder.
- Published
- 2020
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