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Start Over Author "Timm, Sally" Journal american journal of human genetics
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1. Schizophrenia and oxidative stress: Glutamate cysteine ligase modifier as a susceptibility gene

Author

Tosic, Mirjana, Ott, Jurg, Barral, Sandra, Bovet, Pierre, Deppen, Patricia, Gheorghita, Fulvia, Matthey, Marie-Louise, Parnas, Josef, Preisig, Martin, Saraga, Michael, Solida, Alessandra, Timm, Sally, August G. Wang, Werge, Thomas, Cuenod, Michel, and Kim Quang Do

Subjects
Schizophrenia -- Causes of, Schizophrenia -- Genetic aspects, Schizophrenia -- Research, Glutamate -- Research, Genetic susceptibility -- Research, Biological sciences
Abstract

A strong evidence for an association between schizophrenia and the gene of the key Glutathione (GSH)-synthesizing enzyme, glutamate cysteine ligase modifier (GCLM) subunit is presented. It is observed that GSH metabolism dysfunction is proposed as one of the vulnerability factors for schizophrenia.

Published
2006

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