1. Interdialytic Weight Gain: Trends, Predictors, and Associated Outcomes in the International Dialysis Outcomes and Practice Patterns Study (DOPPS)
- Author
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Juergen Bommer, Rajiv Saran, Nathan W. Levin, William M. McClellan, Manfred Hecking, Brian Bieber, Keith McCullough, Tadashi Tomo, Francesca Tentori, Ronald L. Pisoni, Friedrich K. Port, Bruce M. Robinson, and Michelle M.Y. Wong
- Subjects
Male ,Dialysate sodium ,Pediatrics ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,030232 urology & nephrology ,dialysis facility practice patterns ,Interdialytic weight gain (IDWG) ,modifiable risk factor ,030204 cardiovascular system & hematology ,Weight Gain ,03 medical and health sciences ,0302 clinical medicine ,Renal Dialysis ,dialysate sodium ,Internal medicine ,Outcome Assessment, Health Care ,medicine ,Humans ,Prospective Studies ,Practice Patterns, Physicians' ,hospitalizations ,Prospective cohort study ,fluid overload ,Dialysis ,hemodialysis ,Practice patterns ,business.industry ,Proportional hazards model ,Confounding ,sodium gradient ,Middle Aged ,mortality ,3. Good health ,Hospitalization ,end-stage renal disease (ESRD) ,Nephrology ,Kidney Failure, Chronic ,Female ,Hemodialysis ,medicine.symptom ,business ,Weight gain - Abstract
BackgroundHigh interdialytic weight gain (IDWG) is associated with adverse outcomes in hemodialysis (HD) patients. We identified temporal and regional trends in IDWG, predictors of IDWG, and associations of IDWG with clinical outcomes.Study DesignAnalysis 1: sequential cross-sections to identify facility- and patient-level predictors of IDWG and their temporal trends. Analysis 2: prospective cohort study to assess associations between IDWG and mortality and hospitalization risk.Setting & Participants21,919 participants on HD therapy for 1 year or longer in the Dialysis Outcomes and Practice Patterns Study (DOPPS) phases 2 to 5 (2002-2014).PredictorsAnalysis 1: study phase, patient demographics and comorbid conditions, HD facility practices. Analysis 2: relative IDWG, expressed as percentage of post-HD weight (
- Published
- 2016
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