1. Association of Kidney Disease Outcomes With Risk Factors for CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study
- Author
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Yang, Wei, Xie, Dawei, Anderson, Amanda H, Joffe, Marshall M, Greene, Tom, Teal, Valerie, Hsu, Chi-yuan, Fink, Jeffrey C, He, Jiang, Lash, James P, Ojo, Akinlolu, Rahman, Mahboob, Nessel, Lisa, Kusek, John W, Feldman, Harold I, and Investigators, CRIC Study
- Subjects
Prevention ,Clinical Research ,Kidney Disease ,Renal and urogenital ,Adult ,Aged ,Cohort Studies ,Female ,Follow-Up Studies ,Glomerular Filtration Rate ,Humans ,Male ,Middle Aged ,Prospective Studies ,Renal Insufficiency ,Chronic ,Risk Factors ,Treatment Outcome ,Young Adult ,Kidney disease progression ,disease trajectory ,longitudinal outcome ,end-stage renal disease ,estimated glomerular filtration rate ,renal function ,mortality risk ,chronic kidney disease ,Chronic Renal Insufficiency Cohort ,decreased estimated glomerular filtration rate ,CRIC Study Investigators ,Clinical Sciences ,Public Health and Health Services ,Urology & Nephrology - Abstract
BackgroundVarious indicators of progression of chronic kidney disease (CKD) have been used as outcomes in clinical research studies. The effect of using varying measures on the association of risk factors with CKD progression has not been well characterized.Study designProspective cohort study.Setting & participantsThe Chronic Renal Insufficiency Cohort (CRIC) Study (N=3,939) enrolled men and women with mild to moderate CKD, 48% of whom had diabetes and 42% were self-reported black race.PredictorsAge, race, sex, diabetes, baseline estimated glomerular filtration rate (eGFR), proteinuria, and other established CKD risk factors.OutcomesDeath, end-stage renal disease (ESRD), and eGFR events, including: (1) eGFR halving, (2) eGFR
- Published
- 2014