1. Comparing Patient Survival of Home Hemodialysis and Peritoneal Dialysis Patients
- Author
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Choi, Soo Jeong, Obi, Yoshitsugu, Ko, Gang Jee, You, Amy S, Eriguchi, Rieko, Wang, Mengjing, Rhee, Connie M, and Kalantar-Zadeh, Kamyar
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Kidney Disease ,Aging ,Clinical Research ,Renal and urogenital ,Good Health and Well Being ,Adult ,Aged ,Female ,Hemodialysis ,Home ,Humans ,Kidney Failure ,Chronic ,Male ,Middle Aged ,Peritoneal Dialysis ,Registries ,Retrospective Studies ,Survival Analysis ,Time Factors ,Treatment Outcome ,United States ,Home dialysis ,Peritoneal dialysis ,Home hemodialysis ,Urology & Nephrology ,Clinical sciences - Abstract
BackgroundIt is not clear whether peritoneal dialysis (PD) and home hemodialysis (HHD) have similar outcomes, and little is known about how mortality associated with HHD versus PD differs according to the duration of dialysis.MethodsWe examined a national cohort of incident end-stage renal disease patients that was comprised of 1,993 and 16,514 patients transitioning to HHD and PD, respectively, from 2007 to 2011. The HHD patients were matched with PD patients using propensity score (PS). Demographics, comorbidities, duration of dialysis, and body mass index were adjusted for in logistic regression models using PS matching. We matched 1,915 HHD patients with 1,915 PD patients based on the PS. The patients were categorized by their vintage (duration of dialysis) at the time of the transition to HHD or PD (12 months after starting dialysis had an 83% higher risk for mortality (hazard ratio 1.83; 95% CI 1.33-2.52).ConclusionsWhereas there was no meaningful survival difference in the first 12 months between HHD and PD, patients who transitioned to PD after 12 months of dialysis had worse survival than their HHD counterparts. Additional studies are warranted to investigate clinical implications of these differences.
- Published
- 2020