Search

Your search keyword '"Tyrosine cerebrospinal fluid"' showing total 2 results
Start Over Descriptor "Tyrosine cerebrospinal fluid" Journal american journal of psychiatry
2 results on '"Tyrosine cerebrospinal fluid"'

1. CSF neurochemistry of women with anorexia nervosa and normal women.

Author

Gerner RH, Cohen DJ, Fairbanks L, Anderson GM, Young JG, Scheinin M, Linnoila M, Shaywitz BA, and Hare TA

Subjects
Adolescent, Adult, Anorexia Nervosa complications, Body Weight, Calcium cerebrospinal fluid, Choline cerebrospinal fluid, Depressive Disorder cerebrospinal fluid, Depressive Disorder complications, Female, Humans, Hydroxyindoleacetic Acid cerebrospinal fluid, Methoxyhydroxyphenylglycol cerebrospinal fluid, Tryptophan cerebrospinal fluid, gamma-Aminobutyric Acid cerebrospinal fluid, Anorexia Nervosa cerebrospinal fluid, Homovanillic Acid cerebrospinal fluid, Phenylacetates cerebrospinal fluid, Tyrosine cerebrospinal fluid
Abstract

CSF tyrosine, tryptophan, 5-hydroxyindoleacetic acid, 3-methoxy-4-hydroxyphenylglycol (MHPG), homovanillic acid (HVA), gamma-aminobutyric acid, choline, and calcium were compared in 33 anorexic and 14 normal women. The only significant difference between groups was a lower tyrosine level in the anorexic patients; their MHPG level was nonsignificantly higher. No significant group differences in body weight or depressive subgroup were found. HVA levels were positively related to body weight, and choline was negatively correlated with anorexia severity. The role of tyrosine requires further research, but these findings do suggest that HVA and choline increase with some recovery measures and MHPG is increased with this illness.

Published
1984
Full Text
View/download PDF

2. CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls.

Author

Gerner RH, Fairbanks L, Anderson GM, Young JG, Scheinin M, Linnoila M, Hare TA, Shaywitz BA, and Cohen DJ

Subjects
Adolescent, Adult, Age Factors, Aged, Calcium cerebrospinal fluid, Choline cerebrospinal fluid, Female, Homovanillic Acid cerebrospinal fluid, Humans, Hydroxyindoleacetic Acid cerebrospinal fluid, Male, Methoxyhydroxyphenylglycol cerebrospinal fluid, Middle Aged, Research Design, Tryptophan cerebrospinal fluid, Tyrosine cerebrospinal fluid, gamma-Aminobutyric Acid cerebrospinal fluid, Bipolar Disorder cerebrospinal fluid, Depressive Disorder cerebrospinal fluid, Schizophrenia cerebrospinal fluid
Abstract

A total of 114 subjects (41 depressed, 20 schizophrenic, 15 manic, and 38 normal controls) underwent lumbar puncture and their CSF was analyzed for levels of tyrosine, tryptophan, homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), 3-methoxy-4-hydroxyphenylglycol (MHPG), choline, gamma-aminobutyric acid (GABA), and calcium. Results showed that depressed patients, particularly those over 40 years of age, had lower levels of GABA than did controls, and that their level of HVA increased with age, while controls' decreased. Schizophrenic subjects tended to have higher levels of 5-HIAA and manic subjects tended to have higher levels of HVA and MHPG. Age-associated changes were found in HVA, 5-HIAA, MHPG, GABA, and choline concentrations.

Published
1984
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results