1. Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia
- Author
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Wanda K. O'Neal, Rhianna E. Lee, Teresa M. Mascenik, Takanori Asakura, Hong Dang, Lisa C. Morton, Barbara R. Grubb, Hirotoshi Matsui, Martina Gentzsch, Richard C. Boucher, Carlton W Anderson, Kenichi Okuda, Gang Chen, Purushothama Rao Tata, Yvonne K. O’Neal, Satoko Nakano, Takahide Nagase, Yoshihiko Kobayashi, Michael Chua, Selene Margarita Barbosa Cardenas, Nancy L. Quinney, John C. Olsen, Andrew J. Ghio, Gianni Carraro, Caroline E Minnick, Lawrence E. Ostrowski, Rodney C. Gilmore, Takafumi Kato, Scott H. Randell, Barry R. Stripp, and Weining Yin
- Subjects
Pulmonary and Respiratory Medicine ,Cell specific ,congenital, hereditary, and neonatal diseases and abnormalities ,business.industry ,Regulator ,Human airway ,Critical Care and Intensive Care Medicine ,medicine.disease ,Cystic fibrosis ,Transmembrane protein ,Cell biology ,03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,Medicine ,030212 general & internal medicine ,business ,Airway ,Function (biology) - Abstract
Rationale: Identification of the specific cell types expressing CFTR (cystic fibrosis [CF] transmembrane conductance regulator) is required for precision medicine therapies for CF. However, a full ...
- Published
- 2021