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Your search keyword '"Mikael V. Ringh"' showing total 1 results
Start Over Author "Mikael V. Ringh" Journal american journal of respiratory cell and molecular biology
1 results on '"Mikael V. Ringh"'

1. Chronic Obstructive Pulmonary Disease Is Associated with Epigenome-Wide Differential Methylation in BAL Lung Cells

Author

Jonas, Eriksson Ström, Simon, Kebede Merid, Jamshid, Pourazar, Anders, Blomberg, Anne, Lindberg, Mikael V, Ringh, Michael, Hagemann-Jensen, Tomas J, Ekström, Annelie F, Behndig, and Erik, Melén

Subjects
Epigenome, Pulmonary Disease, Chronic Obstructive, Humans, DNA Methylation, Lung, Epigenesis, Genetic, Genome-Wide Association Study
Abstract

DNA methylation patterns in chronic pulmonary obstructive disease (COPD) might offer new insights into disease pathogenesis. To assess methylation profiles in the main COPD target organ, we performed an epigenome-wide association study on BAL cells. Bronchoscopies were performed in 18 subjects with COPD and 15 control subjects (ex- and current smokers). DNA methylation was measured using the Illumina MethylationEPIC BeadChip Kit, covering more than 850,000 CpGs. Differentially methylated positions (DMPs) were examined for

Published
2022

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