1. Gender influences outcomes in trauma patients with elevated systolic blood pressure.
- Author
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Clond MA, Mirocha J, Singer MB, Bukur M, Salim A, Marguiles DR, and Ley EJ
- Subjects
- Adult, Brain Injuries complications, Brain Injuries physiopathology, Female, Follow-Up Studies, Humans, Hypertension complications, Hypertension physiopathology, Incidence, Injury Severity Score, Los Angeles epidemiology, Male, Middle Aged, Morbidity trends, Outcome Assessment, Health Care, Retrospective Studies, Risk Factors, Sex Factors, Survival Rate trends, Blood Pressure, Brain Injuries epidemiology, Hypertension epidemiology
- Abstract
Background: This analysis explored the association between gender and systolic blood pressure (SBP) in trauma patients and then established how gender influenced outcomes in those with elevated SBP., Methods: Demographics and outcomes were compared using the Los Angeles County Trauma System Database and multivariable modeling determined predictors for SBP, pneumonia, and mortality., Results: Age and male sex were significant predictors for increased SBP, whereas the Injury Severity Score (ISS) ≥16 was a significant predictor for decreased SBP. In both male and female TBI patients, SBP ≥160 mmHg was associated with increased pneumonia (Adjusted odds ratio [AOR] = 1.74, P = .002 and AOR = 2.37, P = .046, respectively), whereas SBP ≥160 mmHg was a predictor for mortality only among male TBI patients (AOR = 1.48, P = .03). In non-TBI patients, SBP ≥160 mmHg was not a predictor for pneumonia or mortality in either sex., Conclusions: In this retrospective review of trauma registry data, men presented with higher SBP. In patients with TBI, regardless of gender, increased SBP was associated with increased pneumonia, and in men with TBI increased SBP was associated with increased mortality. The cause and relevance of these epidemiological findings require further investigation., (Crown Copyright © 2011. Published by Elsevier Inc. All rights reserved.)
- Published
- 2011
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