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Your search keyword '"Chen, Ying-Bei"' showing total 21 results
Start Over Author "Chen, Ying-Bei" Journal american journal of surgical pathology
21 results on '"Chen, Ying-Bei"'

3. TFEB Expression Profiling in Renal Cell Carcinomas

Author

Gupta, Sounak, primary, Argani, Pedram, additional, Jungbluth, Achim A., additional, Chen, Ying-Bei, additional, Tickoo, Satish K., additional, Fine, Samson W., additional, Gopalan, Anuradha, additional, Al-Ahmadie, Hikmat A., additional, Sirintrapun, Sahussapont J., additional, Sanchez, Alejandro, additional, Hakimi, Abraham Ari, additional, Mcfarlane, Tiffany, additional, Salazar, Paulo A., additional, Williamson, Sean R., additional, Skala, Stephanie L., additional, Mehra, Rohit, additional, Hes, Ondrej, additional, Antonescu, Cristina R., additional, Ladanyi, Marc, additional, Arcila, Maria E., additional, and Reuter, Victor E., additional

Published
2019
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4. In Organ-confined Prostate Cancer, Tumor Quantitation Not Found to Aid in Prediction of Biochemical Recurrence

Author

Ito, Yujiro, primary, Vertosick, Emily A., additional, Sjoberg, Daniel D., additional, Vickers, Andrew J., additional, Al-Ahmadie, Hikmat A., additional, Chen, Ying-Bei, additional, Gopalan, Anuradha, additional, Sirintrapun, Sahussapont J., additional, Tickoo, Satish K., additional, Eastham, James A., additional, Scardino, Peter T., additional, Reuter, Victor E., additional, and Fine, Samson W., additional

Published
2019
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5. PD-L1 Expression in Urothelial Carcinoma With Predominant or Pure Variant Histology

Author

Reis, Henning, primary, Serrette, Rene, additional, Posada, Jennifer, additional, Lu, Vincent, additional, Chen, Ying-bei, additional, Gopalan, Anuradha, additional, Fine, Samson W., additional, Tickoo, Satish K., additional, Sirintrapun, Sahussapont J., additional, Iyer, Gopa, additional, Funt, Samuel A., additional, Teo, Min Yuen, additional, Rosenberg, Jonathan E., additional, Bajorin, Dean F., additional, Dalbagni, Guido, additional, Bochner, Bernard H., additional, Solit, David B., additional, Reuter, Victor E., additional, and Al-Ahmadie, Hikmat A., additional

Published
2019
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7. VSTM2A Overexpression Is a Sensitive and Specific Biomarker for Mucinous Tubular and Spindle Cell Carcinoma (MTSCC) of the Kidney

Author

Wang, Lisha, primary, Zhang, Yuping, additional, Chen, Ying-Bei, additional, Skala, Stephanie L., additional, Al-Ahmadie, Hikmat A., additional, Wang, Xiaoming, additional, Cao, Xuhong, additional, Veeneman, Brendan A., additional, Chen, Jin, additional, Cieślik, Marcin, additional, Qiao, Yuanyuan, additional, Su, Fengyun, additional, Vats, Pankaj, additional, Siddiqui, Javed, additional, Xiao, Hong, additional, Sadimin, Evita T., additional, Epstein, Jonathan I., additional, Zhou, Ming, additional, Sangoi, Ankur R., additional, Trpkov, Kiril, additional, Osunkoya, Adeboye O., additional, Giannico, Giovanna A., additional, McKenney, Jesse K., additional, Argani, Pedram, additional, Tickoo, Satish K., additional, Reuter, Victor E., additional, Chinnaiyan, Arul M., additional, Dhanasekaran, Saravana M., additional, and Mehra, Rohit, additional

Published
2018
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8. Challenges in Pathologic Staging of Renal Cell Carcinoma

Author

Williamson, Sean R., primary, Rao, Priya, additional, Hes, Ondrej, additional, Epstein, Jonathan I., additional, Smith, Steven C., additional, Picken, Maria M., additional, Zhou, Ming, additional, Tretiakova, Maria S., additional, Tickoo, Satish K., additional, Chen, Ying-Bei, additional, Reuter, Victor E., additional, Fleming, Stewart, additional, Maclean, Fiona M., additional, Gupta, Nilesh S., additional, Kuroda, Naoto, additional, Delahunt, Brett, additional, Mehra, Rohit, additional, Przybycin, Christopher G., additional, Cheng, Liang, additional, Eble, John N., additional, Grignon, David J., additional, Moch, Holger, additional, Lopez, Jose I., additional, Kunju, Lakshmi P., additional, Tamboli, Pheroze, additional, Srigley, John R., additional, Amin, Mahul B., additional, Martignoni, Guido, additional, Hirsch, Michelle S., additional, Bonsib, Stephen M., additional, and Trpkov, Kiril, additional

Published
2018
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9. Comedonecrosis Revisited

Author

Fine, Samson W., primary, Al-Ahmadie, Hikmat A., additional, Chen, Ying-Bei, additional, Gopalan, Anuradha, additional, Tickoo, Satish K., additional, and Reuter, Victor E., additional

Published
2018
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10. Distinct Genomic Copy Number Alterations Distinguish Mucinous Tubular and Spindle Cell Carcinoma of the Kidney From Papillary Renal Cell Carcinoma With Overlapping Histologic Features

Author

Ren, Qinghu, primary, Wang, Lu, additional, Al-Ahmadie, Hikmat A., additional, Fine, Samson W., additional, Gopalan, Anuradha, additional, Sirintrapun, Sahussapont J., additional, Tickoo, Satish K., additional, Reuter, Victor E., additional, and Chen, Ying-Bei, additional

Published
2018
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11. Reappraisal of Morphologic Differences Between Renal Medullary Carcinoma, Collecting Duct Carcinoma, and Fumarate Hydratase–deficient Renal Cell Carcinoma

Author

Ohe, Chisato, primary, Smith, Steven C., additional, Sirohi, Deepika, additional, Divatia, Mukul, additional, de Peralta-Venturina, Mariza, additional, Paner, Gladell P., additional, Agaimy, Abbas, additional, Amin, Mitual B., additional, Argani, Pedram, additional, Chen, Ying-Bei, additional, Cheng, Liang, additional, Colecchia, Maurizio, additional, Compérat, Eva, additional, Werneck da Cunha, Isabela, additional, Epstein, Jonathan I., additional, Gill, Anthony J., additional, Hes, Ondřej, additional, Hirsch, Michelle S., additional, Jochum, Wolfram, additional, Kunju, Lakshmi P., additional, Maclean, Fiona, additional, Magi-Galluzzi, Cristina, additional, McKenney, Jesse K., additional, Mehra, Rohit, additional, Nesi, Gabriella, additional, Osunkoya, Adeboye O., additional, Picken, Maria M., additional, Rao, Priya, additional, Reuter, Victor E., additional, de Oliveira Salles, Paulo Guilherme, additional, Schultz, Luciana, additional, Tickoo, Satish K., additional, Tomlins, Scott A., additional, Trpkov, Kiril, additional, and Amin, Mahul B., additional

Published
2018
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12. Tubulocystic Carcinoma of the Kidney With Poorly Differentiated Foci

Author

Smith, Steven C., primary, Trpkov, Kiril, additional, Chen, Ying-Bei, additional, Mehra, Rohit, additional, Sirohi, Deepika, additional, Ohe, Chisato, additional, Cani, Andi K., additional, Hovelson, Daniel H., additional, Omata, Kei, additional, McHugh, Jonathan B., additional, Jochum, Wolfram, additional, Colecchia, Maurizio, additional, Amin, Mitual, additional, Divatia, Mukul K., additional, Hes, Ondřej, additional, Menon, Santosh, additional, Werneck da Cunha, Isabela, additional, Tripodi, Sergio, additional, Brimo, Fadi, additional, Gill, Anthony J., additional, Osunkoya, Adeboye O., additional, Magi-Galluzzi, Cristina, additional, Sibony, Mathilde, additional, Williamson, Sean R., additional, Nesi, Gabriella, additional, Picken, Maria M., additional, Maclean, Fiona, additional, Agaimy, Abbas, additional, Cheng, Liang, additional, Epstein, Jonathan I., additional, Reuter, Victor E., additional, Tickoo, Satish K., additional, Tomlins, Scott A., additional, and Amin, Mahul B., additional

Published
2016
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13. Atypical Renal Cysts

Author

Matoso, Andres, primary, Chen, Ying-Bei, additional, Rao, Vishal, additional, Wang, Lu, additional, Cheng, Liang, additional, and Epstein, Jonathan I., additional

Published
2016
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16. Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome–associated Renal Cancer

Author

Chen, Ying-Bei, primary, Brannon, A. Rose, additional, Toubaji, Antoun, additional, Dudas, Maria E., additional, Won, Helen H., additional, Al-Ahmadie, Hikmat A., additional, Fine, Samson W., additional, Gopalan, Anuradha, additional, Frizzell, Norma, additional, Voss, Martin H., additional, Russo, Paul, additional, Berger, Michael F., additional, Tickoo, Satish K., additional, and Reuter, Victor E., additional

Published
2014
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17. Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC)

Author

Udager, Aaron M., primary, Alva, Ajjai, additional, Chen, Ying-Bei, additional, Siddiqui, Javed, additional, Lagstein, Amir, additional, Tickoo, Satish K., additional, Reuter, Victor E., additional, Chinnaiyian, Arul M., additional, and Mehra, Rohit, additional

Published
2014
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19. Chromophobe Renal Cell Carcinoma

Author

Przybycin, Christopher G., primary, Cronin, Angel M., additional, Darvishian, Farbod, additional, Gopalan, Anuradha, additional, Al-Ahmadie, Hikmat A., additional, Fine, Samson W., additional, Chen, Ying-bei, additional, Bernstein, Melanie, additional, Russo, Paul, additional, Reuter, Victor E., additional, and Tickoo, Satish K., additional

Published
2011
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21. Atypical Renal Cysts: A Morphologic, Immunohistochemical, and Molecular Study.

Author

Matoso A, Chen YB, Rao V, Wang L, Cheng L, and Epstein JI

Subjects
Adult, Aged, Aged, 80 and over, Baltimore, Biopsy, Carcinoma, Renal Cell chemistry, Carcinoma, Renal Cell genetics, Carcinoma, Renal Cell pathology, Carcinoma, Renal Cell surgery, Female, Genetic Predisposition to Disease, Humans, Kidney Diseases, Cystic genetics, Kidney Diseases, Cystic metabolism, Kidney Diseases, Cystic pathology, Kidney Diseases, Cystic surgery, Kidney Neoplasms chemistry, Kidney Neoplasms genetics, Kidney Neoplasms pathology, Kidney Neoplasms surgery, Male, Middle Aged, Nephrectomy, Phenotype, Precancerous Conditions chemistry, Precancerous Conditions genetics, Precancerous Conditions pathology, Precancerous Conditions surgery, Predictive Value of Tests, Treatment Outcome, Biomarkers, Tumor analysis, Biomarkers, Tumor genetics, Carcinoma, Renal Cell diagnosis, Immunohistochemistry, In Situ Hybridization, Fluorescence, Kidney Diseases, Cystic diagnosis, Kidney Neoplasms diagnosis, Molecular Diagnostic Techniques, Precancerous Conditions diagnosis
Abstract

There is a lack of standardized nomenclature for renal cysts lined by multiple cell layers or with short papillary projections but without nests of epithelial cells within the stroma. We retrieved 29 cases (15 nephrectomies, 14 partial nephrectomies) from the surgical pathology files of Johns Hopkins Hospital from 1993 to 2014 and performed immunohistochemistry for CK7, alpha-methylacyl-CoA racemase (AMACR), CAIX, and CD10 and fluorescence in situ hybridization for trisomy 7 and 17 and 3p deletion. The mean age at excision was 58 years (range, 29 to 80 y) with 16 men and 13 women. Mean size was 2.9 cm (range, 0.3 to 10 cm). The cysts were grouped by their morphology into (1) clear cell, (2) eosinophilic stratified, and (3) eosinophilic papillary. By immunohistochemistry, 7/9 (78%) of the clear cell cases were diffusely positive for both CK7 and CAIX resembling the pattern seen in clear cell papillary renal cell carcinoma. The majority of eosinophilic stratified (4/6; 67%) and eosinophilic papillary (12/14; 86%) cases were positive for CK7 and had variable staining for AMACR, CD10, or CAIX, suggesting a differentiation more aligned with papillary renal cell carcinoma. The most common molecular alterations detected were trisomy 17 (n=6) and trisomy 7 (n=4). One case showed deletion of chromosome 3p. Clinical follow-up information was available in 23 patients; 20 were alive with no evidence of disease after a median follow-up of 20 months (range, 3 to 120 mo), 1 patient was dead due to metastatic lung cancer, 1 of sepsis, and 1 of unknown reason. Atypical renal cysts present as complex radiologic lesions, as secondary lesions in patients with a renal mass, or in a background of chronic renal disease. These atypical cysts appear heterogenous, and some follow in their morphology and immunoprofile with well-established renal tumors. The presence of 3p deletion and trisomy 7/17 suggests that in some cases they may be precursors of renal cell carcinoma. Longer follow-up with more cases is needed, but on the basis of our data, these lesions should not be diagnosed as carcinoma.

Published
2016
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