Search

Your search keyword '"Gopalan, Anuradha"' showing total 19 results
Start Over Author "Gopalan, Anuradha" Journal american journal of surgical pathology
19 results on '"Gopalan, Anuradha"'

2. TFEB Expression Profiling in Renal Cell Carcinomas

Author

Gupta, Sounak, primary, Argani, Pedram, additional, Jungbluth, Achim A., additional, Chen, Ying-Bei, additional, Tickoo, Satish K., additional, Fine, Samson W., additional, Gopalan, Anuradha, additional, Al-Ahmadie, Hikmat A., additional, Sirintrapun, Sahussapont J., additional, Sanchez, Alejandro, additional, Hakimi, Abraham Ari, additional, Mcfarlane, Tiffany, additional, Salazar, Paulo A., additional, Williamson, Sean R., additional, Skala, Stephanie L., additional, Mehra, Rohit, additional, Hes, Ondrej, additional, Antonescu, Cristina R., additional, Ladanyi, Marc, additional, Arcila, Maria E., additional, and Reuter, Victor E., additional

Published
2019
Full Text
View/download PDF

3. In Organ-confined Prostate Cancer, Tumor Quantitation Not Found to Aid in Prediction of Biochemical Recurrence

Author

Ito, Yujiro, primary, Vertosick, Emily A., additional, Sjoberg, Daniel D., additional, Vickers, Andrew J., additional, Al-Ahmadie, Hikmat A., additional, Chen, Ying-Bei, additional, Gopalan, Anuradha, additional, Sirintrapun, Sahussapont J., additional, Tickoo, Satish K., additional, Eastham, James A., additional, Scardino, Peter T., additional, Reuter, Victor E., additional, and Fine, Samson W., additional

Published
2019
Full Text
View/download PDF

4. PD-L1 Expression in Urothelial Carcinoma With Predominant or Pure Variant Histology

Author

Reis, Henning, primary, Serrette, Rene, additional, Posada, Jennifer, additional, Lu, Vincent, additional, Chen, Ying-bei, additional, Gopalan, Anuradha, additional, Fine, Samson W., additional, Tickoo, Satish K., additional, Sirintrapun, Sahussapont J., additional, Iyer, Gopa, additional, Funt, Samuel A., additional, Teo, Min Yuen, additional, Rosenberg, Jonathan E., additional, Bajorin, Dean F., additional, Dalbagni, Guido, additional, Bochner, Bernard H., additional, Solit, David B., additional, Reuter, Victor E., additional, and Al-Ahmadie, Hikmat A., additional

Published
2019
Full Text
View/download PDF

6. Comedonecrosis Revisited

Author

Fine, Samson W., primary, Al-Ahmadie, Hikmat A., additional, Chen, Ying-Bei, additional, Gopalan, Anuradha, additional, Tickoo, Satish K., additional, and Reuter, Victor E., additional

Published
2018
Full Text
View/download PDF

7. Distinct Genomic Copy Number Alterations Distinguish Mucinous Tubular and Spindle Cell Carcinoma of the Kidney From Papillary Renal Cell Carcinoma With Overlapping Histologic Features

Author

Ren, Qinghu, primary, Wang, Lu, additional, Al-Ahmadie, Hikmat A., additional, Fine, Samson W., additional, Gopalan, Anuradha, additional, Sirintrapun, Sahussapont J., additional, Tickoo, Satish K., additional, Reuter, Victor E., additional, and Chen, Ying-Bei, additional

Published
2018
Full Text
View/download PDF

10. Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome–associated Renal Cancer

Author

Chen, Ying-Bei, primary, Brannon, A. Rose, additional, Toubaji, Antoun, additional, Dudas, Maria E., additional, Won, Helen H., additional, Al-Ahmadie, Hikmat A., additional, Fine, Samson W., additional, Gopalan, Anuradha, additional, Frizzell, Norma, additional, Voss, Martin H., additional, Russo, Paul, additional, Berger, Michael F., additional, Tickoo, Satish K., additional, and Reuter, Victor E., additional

Published
2014
Full Text
View/download PDF

12. Chromophobe Renal Cell Carcinoma

Author

Przybycin, Christopher G., primary, Cronin, Angel M., additional, Darvishian, Farbod, additional, Gopalan, Anuradha, additional, Al-Ahmadie, Hikmat A., additional, Fine, Samson W., additional, Chen, Ying-bei, additional, Bernstein, Melanie, additional, Russo, Paul, additional, Reuter, Victor E., additional, and Tickoo, Satish K., additional

Published
2011
Full Text
View/download PDF

13. Prostate Cancer Topography and Patterns of Lymph Node Metastasis

Author

Tokuda, Yuji, primary, Carlino, Lauren J., additional, Gopalan, Anuradha, additional, Tickoo, Satish K., additional, Kaag, Matthew G., additional, Guillonneau, Bertrand, additional, Eastham, James A., additional, Scher, Howard I., additional, Scardino, Peter T., additional, Reuter, Victor E., additional, and Fine, Samson W., additional

Published
2010
Full Text
View/download PDF

14. Urachal Carcinoma

Author

Gopalan, Anuradha, primary, Sharp, David S., additional, Fine, Samson W., additional, Tickoo, Satish K., additional, Herr, Harry W., additional, Reuter, Victor E., additional, and Olgac, Semra, additional

Published
2009
Full Text
View/download PDF

19. Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation.

Author

Gopalan A, Sharp DS, Fine SW, Tickoo SK, Herr HW, Reuter VE, and Olgac S

Subjects
Adenocarcinoma pathology, Adult, Aged, CDX2 Transcription Factor, Carcinoma chemistry, Carcinoma therapy, Carcinoma, Signet Ring Cell pathology, Chemotherapy, Adjuvant, Cystectomy, Cystitis pathology, Databases as Topic, Female, Homeodomain Proteins analysis, Humans, Immunohistochemistry, Keratin-20 analysis, Keratin-7 analysis, Male, Middle Aged, Neoplasm Metastasis, Neoplasm Recurrence, Local, Neoplasm Staging, Radiotherapy, Adjuvant, Treatment Outcome, Umbilicus surgery, Urachus chemistry, Urachus surgery, Urinary Bladder Neoplasms chemistry, Urinary Bladder Neoplasms therapy, Urothelium chemistry, Urothelium surgery, beta Catenin analysis, Carcinoma pathology, Urachus pathology, Urinary Bladder Neoplasms pathology, Urothelium pathology
Abstract

Background: Urachal carcinomas occur mostly in the bladder dome, comprising 22% to 35% of vesical adenocarcinomas, and are generally treated by partial cystectomy with en bloc resection of the median umbilical ligament and umbilicus. Detailed pathologic studies with clinical outcome correlation are few., Design: We reviewed histologic material and clinical data from 24 cases selected from a database of 67 dome-based tumors diagnosed and treated at our institution from 1984 to 2005. Follow-up information was available for all 24 patients., Result: The mean age at diagnosis was 52 years (range: 26 to 68 y). Fifteen patients were male and 9 were female. Location was the dome in 23 and dome and anterior wall in 1. Thirteen cases were pure adenocarcinoma, not otherwise specified, 9 were enteric type adenocarcinoma, and 2 were adenocarcinoma with focal components of lymphoepithelioma-like carcinoma and urothelial carcinoma with cytoplasmic clearing. Signet ring cell features were focally seen in 2 cases. Cystitis cystica and cystitis glandularis were seen in 4 and 2 cases, respectively. In all instances but 1, cystitis cystica/glandularis was focal and predominantly in the bladder overlying the urachal neoplasm. Urachal remnants were identified in 15 cases: the urachal epithelium was benign urothelial-type in 6 cases and showed adenomatous changes in 9. The overlying bladder urothelium was colonized by adenocarcinoma in 3 cases. In all 3, urachal remnants were identified and showed transition from benign to adenomatous epithelium. On immunohistochemistry, these tumors were positive for CK20 and variably positive for CK7 and 34BE12. The majority showed a cytoplasmic membranous staining pattern for beta-catenin, although in 1 case, focal nuclear immunoreactivity was identified. The Sheldon pathologic stage was pT1 in 0, pT2 in 2, pT3a in 8, pT3b in 11, pT3c in 1, pT4a in 1, and pT4b in 1 patient. One patient had a positive soft tissue margin. The mean follow-up period was 40 months (range: 0.3 to 157.6 mo). Seven of 24 (29%) cases recurred locally. The incidence of local recurrence was higher in patients who underwent a partial cystectomy alone (37.5%) versus those who had a more radical surgery (27%). Distant metastases occurred in 9 (37.5%) patients, 4 of whom had no prior local recurrence. Seven patients (29%) died of the disease. All cases with locally recurrent and metastatic disease belonged to stage pT3 or higher., Conclusions: Pathologic stage is an important prognostic factor in urachal carcinoma. Surface urothelial involvement by carcinoma and presence of cystitis cystica/glandularis do not necessarily exclude the diagnosis of urachal carcinoma. Immunostains do not unequivocally discriminate a urachal from a colorectal carcinoma, but diffuse positivity for 34BE12 would support, and diffuse nuclear immunoreactivity for beta-catenin would militate against, a diagnosis of urachal carcinoma. Local recurrence may be owing to seeding within the distal urothelial tract, particularly in tumors with a configuration that is polypoid and which open into the bladder cavity. The type of surgery performed may have an effect on local recurrence despite negative margins of resection.

Published
2009
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results