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Your search keyword '"Zhang Shaobo"' showing total 16 results
Start Over Author "Zhang Shaobo" Journal american journal of surgical pathology
16 results on '"Zhang Shaobo"'

4. Clear Cell Papillary Renal Cell Carcinoma–like Tumors in Patients With Von Hippel-Lindau Disease Are Unrelated to Sporadic Clear Cell Papillary Renal Cell Carcinoma

Author

Williamson, Sean R., primary, Zhang, Shaobo, additional, Eble, John N., additional, Grignon, David J., additional, Martignoni, Guido, additional, Brunelli, Matteo, additional, Wang, Mingsheng, additional, Gobbo, Stefano, additional, Baldridge, Lee Ann, additional, and Cheng, Liang, additional

Published
2013
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5. TFE3 Break-apart FISH Has a Higher Sensitivity for Xp11.2 Translocation–associated Renal Cell Carcinoma Compared With TFE3 or Cathepsin K Immunohistochemical Staining Alone

Author

Rao, Qiu, primary, Williamson, Sean R., additional, Zhang, Shaobo, additional, Eble, John N., additional, Grignon, David J., additional, Wang, Mingsheng, additional, Zhou, Xiao-jun, additional, Huang, Wenbin, additional, Tan, Puay-Hoon, additional, MacLennan, Gregory T., additional, and Cheng, Liang, additional

Published
2013
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7. Multilocular Cystic Renal Cell Carcinoma

Author

Williamson, Sean R., primary, Halat, Shams, additional, Eble, John N., additional, Grignon, David J., additional, Lopez-Beltran, Antonio, additional, Montironi, Rodolfo, additional, Tan, Puay-Hoon, additional, Wang, Mingsheng, additional, Zhang, Shaobo, additional, MacLennan, Gregory T., additional, Baldridge, Lee Ann, additional, and Cheng, Liang, additional

Published
2012
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8. Mixed Epithelial and Stromal Tumors of the Kidney

Author

Kum, Jennifer Bup-Jong, primary, Grignon, David J., additional, Wang, Mingsheng, additional, Zhou, Ming, additional, Montironi, Rodolfo, additional, Shen, Steven S., additional, Zhang, Shaobo, additional, Lopez-Beltran, Antonio, additional, Eble, John N., additional, and Cheng, Liang, additional

Published
2011
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9. Sarcomatoid Carcinoma of the Urinary Bladder

Author

Cheng, Liang, primary, Zhang, Shaobo, additional, Alexander, Riley, additional, MacLennan, Gregory T., additional, Hodges, Kurt B., additional, Harrison, Beth T., additional, Lopez-Beltran, Antonio, additional, and Montironi, Rodolfo, additional

Published
2011
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10. Lymphoepithelioma-like Carcinoma of the Urinary Bladder

Author

Williamson, Sean R., primary, Zhang, Shaobo, additional, Lopez-Beltran, Antonio, additional, Shah, Rajal B., additional, Montironi, Rodolfo, additional, Tan, Puay-Hoon, additional, Wang, Mingsheng, additional, Baldridge, Lee Ann, additional, MacLennan, Gregory T., additional, and Cheng, Liang, additional

Published
2011
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13. Clear Cell Papillary Renal Cell Carcinoma

Author

Gobbo, Stefano, primary, Eble, John N., additional, Grignon, David J., additional, Martignoni, Guido, additional, MacLennan, Gregory T., additional, Shah, Rajal B., additional, Zhang, Shaobo, additional, Brunelli, Matteo, additional, and Cheng, Liang, additional

Published
2008
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15. Urothelial Carcinoma With an Inverted Growth Pattern Can be Distinguished From Inverted Papilloma by Fluorescence In Situ Hybridization, Immunohistochemistry, and Morphologic Analysis

Author

Jones, Timothy D., primary, Zhang, Shaobo, additional, Lopez-Beltran, Antonio, additional, Eble, John N., additional, Sung, Ming-Tse, additional, MacLennan, Gregory T., additional, Montironi, Rodolfo, additional, Tan, Puay-Hoon, additional, Zheng, Suqin, additional, Baldridge, Lee Ann, additional, and Cheng, Liang, additional

Published
2007
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16. Nephroblastoma arising in a germ cell tumor of testicular origin.

Author

Emerson RE, Ulbright TM, Zhang S, Foster RS, Eble JN, and Cheng L

Subjects
Adult, Chromosomes, Human, Pair 11 genetics, Chromosomes, Human, Pair 17 genetics, Clone Cells, DNA, Neoplasm analysis, Germinoma genetics, Germinoma surgery, Humans, Loss of Heterozygosity, Lymph Nodes pathology, Lymph Nodes surgery, Male, Microsatellite Repeats genetics, Neoplasms, Second Primary genetics, Neoplasms, Second Primary surgery, Orchiectomy, Polymerase Chain Reaction, Teratoma genetics, Teratoma pathology, Teratoma surgery, Testicular Neoplasms genetics, Testicular Neoplasms surgery, Wilms Tumor genetics, Wilms Tumor surgery, Germinoma pathology, Neoplasms, Second Primary pathology, Testicular Neoplasms pathology, Wilms Tumor pathology
Abstract

We report a nephroblastoma arising in a germ cell tumor of testicular origin occurring in a 22-year-old man. Orchiectomy demonstrated a malignant mixed germ cell tumor composed of mature and immature teratoma with nephroblastoma and rhabdomyosarcoma. Following chemotherapy, the patient developed supraclavicular and retroperitoneal lymphadenopathy. Excision demonstrated metastatic teratoma at both sites. No recurrence was noted with 21 months of additional follow-up. Using tissue microdissection and loss of heterozygosity analysis, we investigated the clonality of the mature teratoma, immature teratoma, nephroblastoma, and rhabdomyosarcoma components of the primary tumor and of the metastatic mature teratoma at the two separate distant sites. Nine microsatellite polymorphic makers were used to examine the pattern of allelic loss in both primary and metastatic tumors. Loss of heterozygosity was found in 4 DNA loci, and the same pattern of allelic loss was demonstrated at all 4 loci in all of the different components of the primary tumor and the metastatic mature teratomas, supporting the germ cell tumor origin of the nephroblastoma component. Loss of heterozygosity on chromosome 17p13 (TP53) was detected in metastatic mature teratoma, but not in the primary tumor. Loss of heterozygosity was observed at 11p13, the locus of WT1 inactivation in patients genetically predisposed to nephroblastoma, and this loss may be an important genetic mechanism in nephroblastomatous differentiation of germ cell tumors. These data support a common clonal origin for nephroblastoma and the other germ cell tumor components.

Published
2004
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