1. Blood transfusion delay and outcome in county hospitals in Kenya
- Author
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Morris Ogero, Mercy Chepkirui, Philip Ayieko, Grace Irimu, Jacquie Oliwa, Mike English, Boniface Makone, Wycliffe Nyachiro, Susan Gachau, Julius Thomas, George Mbevi, and Lucas Malla
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,Time Factors ,Blood transfusion ,Anemia ,medicine.medical_treatment ,Treatment outcome ,030204 cardiovascular system & hematology ,Severe anemia ,03 medical and health sciences ,0302 clinical medicine ,Virology ,Clinical information ,medicine ,Humans ,Blood Transfusion ,030212 general & internal medicine ,business.industry ,Infant ,Articles ,medicine.disease ,Kenya ,3. Good health ,Treatment Outcome ,Infectious Diseases ,Child, Preschool ,Hospital admission ,Female ,Parasitology ,Hemoglobin ,business ,Clinical record - Abstract
Severe anemia is a leading indication for blood transfusion and a major cause of hospital admission and mortality in African children. Failure to initiate blood transfusion rapidly enough contributes to anemia deaths in sub-Saharan Africa. This article examines delays in accessing blood and outcomes in transfused children in Kenyan hospitals. Children admitted with nonsurgical conditions in 10 Kenyan county hospitals participating in the Clinical Information Network who had blood transfusion ordered from September 2013 to March 2016 were studied. The delay in blood transfusion was calculated from the date when blood transfusion was prescribed to date of actual transfusion. Five percent (2,875/53,174) of admissions had blood transfusion ordered. Approximately half (45%, 1,295/2,875) of children who had blood transfusion ordered at admission had a documented hemoglobin < 5 g/dl and 36% (2,232/6,198) of all children admitted with a diagnosis of anemia were reported to have hemoglobin < 5 g/dL. Of all the ordered transfusions, 82% were administered and documented in clinical records, and three-quarters of these (75%, 1,760/2,352) were given on the same day as ordered but these proportions varied from 71% to 100% across the 10 hospitals. Children who had a transfusion ordered but did not receive the prescribed transfusion had a mortality of 20%, compared with 12% among those transfused. Malaria-associated anemia remains the leading indication for blood transfusion in acute childhood illness admissions. Delays in transfusion are common and associated with poor outcomes. Variance in delay across hospitals may be a useful indicator of health system performance.
- Published
- 2016