1. Effects of timolol ophthalmic solution on the intra-ocular pressure rise induced by suxamethonium and tracheal intubation
- Author
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J. N. McGalliard, S. R. W. Bricker, N. P. Mercert, Gregory T. Smith, R. B. Trimble, and S. M. Mostafa
- Subjects
Adult ,medicine.medical_specialty ,Premedication ,medicine.medical_treatment ,Timolol ,Succinylcholine ,Ophthalmologic Surgical Procedures ,Timolol Ophthalmic Solution ,Double-Blind Method ,Intubation, Intratracheal ,medicine ,Humans ,Saline ,Aged ,Ophthalmic surgery ,business.industry ,Significant difference ,Tracheal intubation ,Middle Aged ,Surgery ,Anesthesiology and Pain Medicine ,Intra ocular pressure ,Anesthesia ,Ocular Hypertension ,Ophthalmic Solutions ,business ,Complication ,medicine.drug - Abstract
Summary Thirtv patients received topical application of either timolol ophthalmic solution 0.25%, or normal saline, 2 h before elective ophthalmic surgery in a double-blind study. The responses to suxamethonium and tracheal intubation were compared by measuring intra-ocular pressure before induction of anaesthesia, 1 mm after administration of thiopentone 2–4 mg·kg−1 min after administration of suxamethonium 1 mg·kg−1, and I, 2.5 and 5 min after tracheal intubation. There was no significant difference between the groups.
- Published
- 1992
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