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The presented case report describes the first use of adenosine-induced transient circulatory arrest in a patient undergoing cerebral aneurysm clipping in the Czech Republic. Short episodes of circulatory arrest improved surgical conditions (as assessed by the surgeon) without any apparent complications during surgery. The cumulative length of circulatory arrest was 47 seconds; the total dose of administered adenosine was 90 mg. The postoperative course was uneventful and the patient was discharged home with a good functional status. Current scientific evidence in this field and key practical points of this technique are discussed. [ABSTRACT FROM AUTHOR]