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Sweet’s syndrome is a rare dermatosis with little-known pathogenesis, associated with some clinical conditions such as infections, autoimmune diseases, inflammatory bowel diseases, vaccination, medications and neoplasms. Hematologic malignancies are the diseases most related to paraneoplastic Sweet’s syndrome, but this clinical entity can also be found occasionally in some solid tumors, including genitourinary tract tumors. We report a rare case of paraneoplastic Sweet’s syndrome associated with the diagnosis of cervical cancer.

The incidence of cutaneous metastases is approximately 0.7 to 10%, while in metastases of urothelial origin the incidence is less than 1%. Transitional cell carcinoma is the most common of the genitourinary tract tumors. Sarcoma of the bladder is rare (0.3%). It can involve multiple clinical presentations, with a nodule being the most common. Diagnosis is made by a combination of medical history, clinical examination and histopathology. The treatment is surgical. The prognosis is very uncertain and depends on a multidisciplinary approach.