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Start Over Author "Pedro Farinha" Journal anais brasileiros de dermatologia
2 results on '"Pedro Farinha"'

1. Blastic plasmacytoid dendritic cell neoplasm

Author

André Lencastre, Joana Cabete, Alexandre João, Pedro Farinha, Gilda Ferreira, and Sara Lestre

Subjects
Antigens, CD4, Antigens, CD56, Dendritic cells, Leukemia, Leukemic infiltration, Dermatology, RL1-803
Abstract

Blastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination. We report the case of a 76-year-old man with a 2 month history of violaceous nodules and a tumor with stony consistency, located on the head, and mandibular, cervical and supraclavicular lymphadenopathies. Multiple thoracic and abdominal adenopathies were identified on computerized tomography. Flow cytometry analysis of the skin, lymph node and bone marrow biopsies demonstrated the presence of plasmocytoid dendritic cell neoplastic precursor cells (CD4+, CD45+, CD56+ and CD123+ phenotype). After initial clinical and laboratorial complete remission with chemotherapy, the patient died due to relapse of the disease associated with the appearance of a cervical mass with medullary compromise.

Published
2013
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2. Neoplasia Blástica de Células Dendríticas Plasmocitóides

Author

Sara Lestre, Pedro Farinha, Alexandre João, André Lencastre, Joana Cabete, and Gilda Ferreira

Subjects
Male, Citometria de Fluxo, Pathology, medicine.medical_specialty, Skin Neoplasms, Medullary cavity, Leucemia/Patologia, Invasão Neoplásica, Biopsy, medicine.medical_treatment, Resultado Fatal, Case Report, Antigens, CD56, Dermatology, Células Dendríticas, Antigens, CD4, HSAC DER, Fatal Outcome, Bone Marrow, Humans, Medicine, Neoplasm Invasiveness, Lymph node, Aged, Skin, Pele, Leukemic Infiltration, Chemotherapy, Leukemia, medicine.diagnostic_test, business.industry, Medula Óssea, Dendritic Cells, Dendritic cell, Flow Cytometry, medicine.disease, Biópsia, medicine.anatomical_structure, RL1-803, Neoplasias da Pele, Bone marrow, Leukemic infiltration, business
Abstract

Blastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination. We report the case of a 76-year-old man with a 2 month history of violaceous nodules and a tumor with stony consistency, located on the head, and mandibular, cervical and supraclavicular lymphadenopathies. Multiple thoracic and abdominal adenopathies were identified on computerized tomography. Flow cytometry analysis of the skin, lymph node and bone marrow biopsies demonstrated the presence of plasmocytoid dendritic cell neoplastic precursor cells (CD4+, CD45+, CD56+ and CD123+ phenotype). After initial clinical and laboratorial complete remission with chemotherapy, the patient died due to relapse of the disease associated with the appearance of a cervical mass with medullary compromise.

Published
2013

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