1. Electrochemical detection of dopamine by a calixarene-cellulose acetate mixed Langmuir-Blodgett monolayer.
- Author
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Xu, Yujuan, Hao, Qingli, and Mandler, Daniel
- Subjects
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ELECTROCHEMICAL sensors , *DOPAMINE , *CALIXARENES , *CELLULOSE acetate , *MONOMOLECULAR films - Abstract
Abstract The sensing performance of a Langmuir-Blodgett monolayer was significantly improved by controlling the film organization at the air-water interface. Cellulose acetate (CA) and 4-tert-butylcalix [6]arene (calix) were co-spread and formed a Langmuir film, which was efficiently transferred onto a preoxidized gold electrode, Au ox. The modified gold electrode was applied as a fast, highly sensitive electrochemical sensing platform for the quantitative determination of a model molecule, dopamine (DA). The modified gold electrode, CA-calix/Au ox , demonstrated better recognition and sensing ability towards dopamine as compared with electrodes modified by a single component. Under the optimized conditions, the reduction peak currents at the CA-calix/Au ox increased linearly within the concentration range of dopamine from 5 to 100 and 100–7500 nM, and exhibited a very low limit of detection (LOD) of 2.54 nM (S/N = 3). These results suggest a simple, superior and efficient approach for the controllable rearrangement of Langmuir-Blodgett monolayers on a molecular level. The electroanalytical performance was optimized from the perspective of the electrode-electrolyte interface. Graphical abstract Image 1 Highlights • A mixed Langmuir layer composed of cellulose acetate, and the selectivity factor, calixarene, were co-spread at the air-water interface. • The Langmuir film was transferred onto a solid gold electrode and used as a means of electrochemically detecting dopamine. • The Langmuir-Blodgett based interface was carefully studied and exhibits superior electrochemical performance for the detection of dopamine. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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