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Nanozymes have been relatively well explored, and bimetal-doped nanozymes have attracted much exploration due to their superior catalytic activity. We developed bimetallic FeCu/NPCs and Cu/NPCs nanozymes, which have good catalytic properties due to the coordination of Fe and Cu with N and P. The nanozymes acted as sensing elements in a cascade reaction system to effectively recognize seven terpenoids, including menthol (Men), paeoniflorin (Pae), camphor (Cam), paclitaxel (Pac), andrographolide (Andro), ginkgolide A (Gin A), and piperone (Pip). Terpenoids act as inhibitors of acetylcholinesterase (AChE) and reduce the hydrolysis of acetylcholine (ATCh), providing insight into establishing a simple and distinct assay for terpenoids. Notably, the sensor array distinguished seven terpenoids with concentrations as low as 10 ng/mL and achieved high-precision detection of mixed samples with different molar ratios and 21 unknown samples. Finally, the sensor array successfully distinguished and identified multiple terpenoids in herbal samples. [Display omitted] • A bimetallic and multi-atom co-doped nanozyme was synthesized. Due to the coordination of metal and N, P, the peroxidase activity is much higher than other reported nanozymes. • A simple P doping strategy for pyrolysis of polymer spheres at high temperature was designed. P doping not only formed uniform pore structure, and achieve high coordination with the metal, significantly enhance the catalytic activity of the material • Based on the good activity of nanozymes, different terpenoids have different inhibitory effects on acetylcholinesterase. A colorimetric array sensor for seven terpenoids was constructed. • 4. The sensor array can distinguish 7 terpenoids with a concentration as low as 10 ng / mL in actual Chinese herbal medicine samples, and the discrimination degree reaches 100 %。 [ABSTRACT FROM AUTHOR]