Search

A novel nano-sized copper oxide modified carbon paste electrode has been fabricated to determine the amikacin by cyclic voltammetry and amperometry. The oxidation current of the amikacin on nano-sized copper oxide modified carbon paste electrode was about 40 times higher than that on bulk CuO modified carbon paste electrode. The curve of i vs. concentration was linear in the range of 2–200 µM of the amikacin concentration with a correlation coefficient of 0.998. The detection limit was ca. 1 µM of amikacin with the signal to noise ratio of 3. [ABSTRACT FROM AUTHOR]

An electrochemical immunosensor has been constructed by the self-assemble technique and studied by the AC impedance and potential method respectively. The change of the surface impedance shows that the antibody can be assembled on the electrode surface and recognize the antigen. The gold nanoparticles are not only used to immobilize the CRP antibody, but also can amplify the potential response. The immunosensor responds to antigen in the linear range from 5 to 25 µg/mL and can meet the needs of clinical assay. [ABSTRACT FROM AUTHOR]