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The reduction of luvastatin (FLV) at a hanging mercury-drop electrode (HMDE) was studied by square-wave adsorptive-stripping voltammetry (SWAdSV). FLV can be accumulated and reduced at the electrode, with a maximum peak current intensity at a potential of approximately -1.26 V vs. AgCl/Ag, in an aqueous electrolyte solution of pH 5.25. The method shows linearity between peak current intensity and FLV concentration between 1.0 × 10-8 and 2.7 × 10-6 mol L-1. Limits of detection (LOD) and quantification (LOQ) were found to be 9.9 × 10-9 mol L-1 and 3.3 × 10-8 mol L-1, respectively. Furthermore, FLV oxidation at a glassy carbon electrode surface was used for its hydrodynamic monitoring by amperometric detection in a flow-injection system. The amperometric signal was linear with FLV concentration over the range 1.0 × 10-6 to 1.0 × 10-5 mol L-1, with an LOD of 2.4 × 10-7 mol L-1 and an LOQ of 8.0 × 10-7 mol L-1. A sample rate of 50 injections per hour was achieved. Both methods were validated and showed to be precise and accurate, being satisfactorily applied to the determination of FLV in a commercial pharmaceutical. [ABSTRACT FROM AUTHOR]