1. Is there a Clinically Useful Relationship between Testosterone and Prostate Specific Antigen in Patients with Lower Urinary Tract Symptoms?
- Author
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Arif Akhtar, Rajeev Sood, Raman Tanwar, and Nikhil Khattar
- Subjects
Gynecology ,medicine.medical_specialty ,business.industry ,Urology ,Testosterone (patch) ,Retrospective cohort study ,General Medicine ,urologic and male genital diseases ,Omics ,medicine.disease ,Prostate-specific antigen ,medicine.anatomical_structure ,Antigen ,Prostate ,Lower urinary tract symptoms ,Cohort ,medicine ,business - Abstract
Introduction: Relationship between Testosterone and Prostate Specific Antigen (PSA) in patients with Lower urinary Tract Symptoms (LUTS) is ambiguous. The present study aims to establish the relationship of these variables in patients with LUTS, with a larger study cohort. Methods: A retrospective study was done over a period of 4 years at a tertiary care center. Free and total PSA were correlated with age, prostate volume and Testosterone using appropriate statistical tests in 1156 patients. Patients were stratified into two groups based on PSA level of 4 ng/ml and correlation was studied separately. Results: A weak negative correlation was present between free PSA and Testosterone levels (-0.182, p 4 ng/ml but a weak negative correlation was found between free PSA and Testosterone (-0.156, p
- Published
- 2015
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