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Your search keyword '"Roman S. Erdmann"' showing total 2 results
Start Over Author "Roman S. Erdmann" Journal angewandte chemie
2 results on '"Roman S. Erdmann"'

1. Switchable Proline Derivatives: Tuning the Conformational Stability of the Collagen Triple Helix by pH Changes

Author

Roman S. Erdmann, Helma Wennemers, and Christiane Siebler

Subjects
Proline, Stereochemistry, Chemistry, 010405 organic chemistry, Collagen helix, Circular Dichroism, Hydrogen Bonding, Stereoisomerism, General Chemistry, General Medicine, Hydrogen-Ion Concentration, Ring (chemistry), Ph changes, 010402 general chemistry, 01 natural sciences, Catalysis, Protein Structure, Secondary, Protein Structure, Tertiary, 0104 chemical sciences, Conformational stability, Collagen, Triple helix
Abstract

(4S)-Aminoproline is introduced as a pH-sensitive probe for tuning the conformational properties of peptides and proteins. The pH-triggered flip of the ring puckering and the formation/release of a transannular H bond were used to switch the formation of collagen triple helices on and off reversibly.

Published
2014
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2. Importance of Ring Puckering versus Interstrand Hydrogen Bonds for the Conformational Stability of Collagen

Author

Helma Wennemers and Roman S. Erdmann

Subjects
Models, Molecular, Protein Denaturation, Proline, Chemistry, Stereochemistry, Hydrogen bond, Protein Conformation, Protein Stability, Hydrogen Bonding, General Chemistry, Protein engineering, General Medicine, Ring (chemistry), Catalysis, Protein Structure, Secondary, Animals, Humans, Thermodynamics, Conformational stability, Collagen, Polyproline helix
Published
2011
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