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Your search keyword '"Vancomycin chemical synthesis"' showing total 3 results
Start Over Descriptor "Vancomycin chemical synthesis" Journal angewandte chemie international ed in english
3 results on '"Vancomycin chemical synthesis"'

1. Antimicrobial surfaces through natural product hybrids.

Author

Wach JY, Bonazzi S, and Gademann K

Subjects
Anhydrides chemistry, Anti-Infective Agents chemical synthesis, Bacillus subtilis cytology, Bacillus subtilis drug effects, Dimethylformamide, Fluorenes chemistry, Formamides chemistry, Levodopa chemistry, Microscopy, Fluorescence, Oxides chemistry, Propionates chemistry, Quinolinium Compounds chemical synthesis, Surface Properties, Titanium chemistry, Vancomycin chemical synthesis, Vancomycin chemistry, Vancomycin pharmacology, Anti-Infective Agents chemistry, Anti-Infective Agents pharmacology, Biological Products chemistry, Quinolinium Compounds chemistry, Quinolinium Compounds pharmacology, Vancomycin analogs & derivatives
Published
2008
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2. A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: a case study of vancomycin.

Author

Ritter TK, Mong KK, Liu H, Nakatani T, and Wong CH

Subjects
Anti-Bacterial Agents chemical synthesis, Anti-Bacterial Agents chemistry, Biological Products chemical synthesis, Biological Products chemistry, Glycosylation, Molecular Structure, Nitrogen chemistry, Oligosaccharides chemistry, Vancomycin analogs & derivatives, Oligosaccharides chemical synthesis, Vancomycin chemical synthesis, Vancomycin chemistry
Published
2003
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3. Vancomycin assembly: nature's way.

Author

Hubbard BK and Walsh CT

Subjects
Anti-Bacterial Agents chemical synthesis, Anti-Bacterial Agents chemistry, Bacteria drug effects, Bacteria genetics, Bacteria metabolism, Drug Resistance, Bacterial, Gene Expression Regulation, Bacterial, Glycosylation, Vancomycin chemical synthesis, Vancomycin chemistry, Anti-Bacterial Agents biosynthesis, Anti-Bacterial Agents pharmacology, Vancomycin biosynthesis, Vancomycin pharmacology
Abstract

Antibiotics are precious resources in the fight to combat bacterial infections caused by pathogenic organisms. Vancomycin is one of the antibiotics of last resort in the treatment of life-threatening infections by gram-positive bacteria. The rules by which nature assembles the glycopeptide (vancomycin) and lipoglycopeptide (teicoplanin) antibiotics are becoming elucidated and verified: first amino acids are synthesized, then joined together and cross-linked. This knowledge opens up approaches for reprogramming strategies at the level of altered monomers, swapped assembly lines, and different post-assembly tailoring enzymes.

Published
2003
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