1. Can Thrombus Burden Predict Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction?
- Author
-
Sigirci, Serhat, Keskin, Kudret, Yildiz, Süleyman Sezai, Cetinkal, Gökhan, Gurdal, Ahmet, Kilci, Hakan, Tezcan, Mehmet, and Kilickesmez, Kadriye Orta
- Subjects
KIDNEY disease risk factors ,AGE distribution ,CORONARY disease ,GLOMERULAR filtration rate ,HEMOGLOBINS ,HYPERTENSION ,MULTIVARIATE analysis ,MYOCARDIAL infarction ,THROMBOLYTIC therapy ,MULTIPLE regression analysis ,CONTRAST media ,CORONARY angiography ,PERCUTANEOUS coronary intervention ,VENTRICULAR ejection fraction - Abstract
The incidence of contrast-induced nephropathy (CIN) increases in the range from patients with unstable angina to ST-segment elevation myocardial infarction (STEMI). Platelet activation has been associated with pathophysiology of nephropathy and thrombus burden in the infarct-related arteries. We investigated the impact of thrombus burden on CIN in patients with STEMI. We enrolled 883 patients with STEMI who received primary percutaneous coronary intervention. Patients were divided into groups according to thrombus burden and CIN development. Thrombus burden was scored based on thrombolysis in myocardial infarction thrombus grades (TGs). Thrombus grade 4 was defined as large thrombus burden (LTB), while thrombus burden
- Published
- 2019
- Full Text
- View/download PDF