1. The Association Between High-Sensitivity C-Reactive Protein/Albumin Ratio and Cardiovascular Prognosis in Patients Undergoing Percutaneous Coronary Intervention
- Author
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Jie Yang, Chen Li, Yitian Zheng, Jun Gao, Yu Peng Liu, Jing jia Wang, Jing jing Song, Qing Zhou, Xiangbin Meng, Kuo Zhang, Wenyao Wang, Chunli Shao, and Yi-Da Tang
- Subjects
C-Reactive Protein ,Percutaneous Coronary Intervention ,Treatment Outcome ,Risk Factors ,Humans ,Drug-Eluting Stents ,Coronary Artery Disease ,Cardiology and Cardiovascular Medicine ,Prognosis - Abstract
Limited studies have focused on the impact of high-sensitivity C-reactive protein (hsCRP) to albumin ratio (CAR) on cardiovascular outcomes in patients undergoing percutaneous coronary intervention (PCI). Hence, the present study evaluates the association between CAR and cardiovascular outcomes in patients undergoing drug-eluting stent (DES) implantation. We consecutively enrolled 9375 CHD patients undergoing DES implantation. All patients were divided into 3 groups according to their CAR: tertile 1 (CAR ≤.02, n=3125), tertile 2 (.02.06, n = 3125). The primary endpoint was major adverse cardiovascular and cerebrovascular events (MACCE). Kaplan-Meier analysis indicated that the incidences of MACCE and MI increased with high tertiles of the CAR (MACCE: 8.7 vs 10.5 vs 12.3%, log-rank P < .001; MI: 3.3 vs 4.0 vs 4.7%, long-rank P = .015). Cox regression analysis suggested that CAR was an independent risk factors for MACCE (HR per standard deviation (SD) increase: 1.07, 95% CI, 1.01–1.14, P = .024), and MI (HR per SD increase: 1.11, 95% CI, 1.01–1.22, P = .028). In conclusion, the CAR is an independent predictor of MACCE and MI in CHD patients.
- Published
- 2022