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The study on eastern woodrats, Neotoma floridana, shows no sign of sex-biased maternal investment in response to nutritional stress for this species despite a strong effect on growth rates of offspring from nutritionally controlled litters compared with those from control groups. Stressed dams can rear a single young with slight or no decrease in growth rates of the young compared with those of unstressed dams by mobilizing body reserves but growth rates are reduced from larger litters.