1. Genome‐wide association study identifies a novel candidate gene for egg production traits in chickens.
- Author
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Kang, Huimin, Lu, Yuedan, Zhang, Weitu, Hua, Guohong, Gan, Jiankang, Deng, Xuqing, Zhang, Zhengfen, and Li, Hua
- Subjects
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AGRICULTURAL egg production , *GENOME-wide association studies , *CHICKEN breeds , *POULTRY breeding , *CHICKENS , *EGGS , *SINGLE nucleotide polymorphisms , *GENES - Abstract
Qingyuan partridge chicken is a renowned indigenous yellow broiler breed in China. Egg production traits are important economic traits for chickens. With the decreasing cost of whole genome resequencing, identifying candidate genes with more precision has become possible. In order to identify molecular markers and candidate genes associated with egg production traits, we conducted genome‐wide association studies based on the resequencing data of 287 female Qingyuan partridge chickens. For each hen, age at first egg and egg laying rate were recorded and calculated, respectively. With a univariate linear mixed model, we detected one genome‐wide significant single nucleotide polymorphism (SNP) and three chromosome‐wide significant SNPs associated with egg laying rate. MTA2 is highly likely to be a functional gene for egg laying rate. Our study identifies MTA2 as the first time to be associated with egg laying rate. Findings in our study will advance our understanding of the genetic basis of egg production and have the potential to improve the efficiency of genomic selection in chickens. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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