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Equine atypical myopathy (EAM) is an acute, severe rhabdomyolysis associated with ingestion of hypoglicyn A contained in seeds and seedlings of Sycamore maple (Acer pseudoplatanus). An increasing number of outbreaks has been reported in recent years, including some from countries where the disease has not been previously diagnosed. EAM occurs predominantly during the autumn and less often in the spring. Treatment plans can be extrapolated from the described clinical signs and metabolic problems, but they remain limited to supportive care. Since treatment is still unsuccessful in the majority of cases, the main emphasis is currently still on prevention. In this review, clinical and other details of EAM are analysed. [ABSTRACT FROM AUTHOR]